10-7570-25

antibody from ABEOMICS Inc.
Targeting: ENG CD105, END, HHT1, ORW, ORW1
Provider product page for 10-7570-25

Antibody data

Product number
10-7570-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Endoglin Antibody
Antibody type
Monoclonal
Description
ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A partial length recombinant Endogl
in protein (amino acids 43-287) was
used as the immunogen for this ant
ibody.
Isotype
IgG
Antibody clone number
ABM46D3
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
ENG protein structure - 10-7570-25 shown in red.