BS8296

antibody from Bioworld Technology, Inc
Targeting: HAGH GLO2, GLXII, HAGH1
Provider product page for BS8296
Western blot
Immunohistochemistry

Antibody data

Product number
BS8296 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HAGH polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HAGH.
Description
The glyoxal pathway plays a role in the detoxification of glucose degradation products (GDP). Glyoxalase I and Gyloxalase II (also designated hydroxyacyl glutathione hydrolase or HAGH) are members of the Gyloxalase family. The Gyloxalase II enzyme is a thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form reduced glutathione and D-lactic acid. It exists only as a monomer and binds two zinc ions per subunit. Glyoxalase II contains 260 amino acids. It is detected in the mitochondria and cytosol of mammals. Both Glyoxalase I and Gyloxalase II are detected at a higher activity level in breast cancer tissues than with matched unaffected tissues. This suggests that glyoxalase inhibitor drugs may be effective in the treatment of cancer.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HAGH protein structure - BS8296 shown in red.