NBP1-20250

antibody from Novus Biologicals

Targeting: HCN1 BCNG-1, BCNG1, HAC-2

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

NBP1-20250

Provider

Novus Biologicals

Proper citation

Novus Cat#NBP1-20250, RRID:AB_1642226

Product name

Sheep Polyclonal HCN1 Antibody

Antibody type

Polyclonal

Description

Unpurified. HCN1.

Reactivity

Human, Mouse, Rat

Host

Sheep

Isotype

IgG

Vial size

0.1 ml

Concentration

LYOPH

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

References

Submitted references

Cerebral ischemia-reperfusion causes a down regulation of HCN1 expression via enhancing the nuclear NRSF-HDAC4 gathering that contributes to neuron damage.

Luo P, Fu X, Chang M, Zhang L, Guo L
Brain research bulletin 2020 Mar;156:50-57

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Downregulation of HCN1 channels in hippocampus and prefrontal cortex in methamphetamine re-exposed mice with enhanced working memory.

Zhou M, Lin K, Si Y, Ru Q, Chen L, Xiao H, Li C
Physiological research 2019 Mar 6;68(1):107-117

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Baclofen ameliorates spatial working memory impairments induced by chronic cerebral hypoperfusion via up-regulation of HCN2 expression in the PFC in rats.

Luo P, Chen C, Lu Y, Fu T, Lu Q, Xu X, Li C, He Z, Guo L
Behavioural brain research 2016 Jul 15;308:6-13

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Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region.

Luo P, Lu Y, Li C, Zhou M, Chen C, Lu Q, Xu X, He Z, Guo L
Neurobiology of learning and memory 2015 Sep;123:72-83

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Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure.

Zhou M, Luo P, Lu Y, Li CJ, Wang DS, Lu Q, Xu XL, He Z, Guo LJ
Progress in neuro-psychopharmacology & biological psychiatry 2015 Jan 2;56:207-14

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Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion.

Li CJ, Lu Y, Zhou M, Zong XG, Li C, Xu XL, Guo LJ, Lu Q
Molecular neurobiology 2014 Oct;50(2):704-20