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- Antibody Data
- Antigen structure
- References [11]
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- Product number
- MAB1547-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse NKG2D/CD314 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse NKG2D in direct ELISAs and Western blots. Does not cross-react with recombinant human NKG2D.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
O54709- Isotype
- IgG
- Antibody clone number
- 191004
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references NKG2D ligand RAE1ε induces generation and enhances the inhibitor function of myeloid-derived suppressor cells in mice.
NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity.
HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing.
NKG2D triggers cytotoxicity in murine epidermal γδ T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway.
CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.
CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation.
Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor γδ are involved in bacterial clearance during Salmonella enterica serovar Typhimurium infection.
Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties.
Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells.
Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D.
Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease.
Qian L, Liu Y, Wang S, Gong W, Jia X, Liu L, Ye F, Ding J, Xu Y, Fu Y, Tian F
Journal of cellular and molecular medicine 2017 Sep;21(9):2046-2054
Journal of cellular and molecular medicine 2017 Sep;21(9):2046-2054
NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity.
Nielsen MM, Dyring-Andersen B, Schmidt JD, Witherden D, Lovato P, Woetmann A, Ødum N, Poulsen SS, Havran WL, Geisler C, Bonefeld CM
The Journal of investigative dermatology 2015 May;135(5):1311-1319
The Journal of investigative dermatology 2015 May;135(5):1311-1319
HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing.
Ham H, Huynh W, Schoon RA, Vale RD, Billadeau DD
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3984-96
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3984-96
NKG2D triggers cytotoxicity in murine epidermal γδ T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway.
Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara-Takeuchi A, Kuroki K, Kajikawa M, Ose T, Maenaka K, Kasahara M, Kanekura T
The Journal of investigative dermatology 2014 Feb;134(2):396-404
The Journal of investigative dermatology 2014 Feb;134(2):396-404
CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.
Hosomi S, Chen Z, Baker K, Chen L, Huang YH, Olszak T, Zeissig S, Wang JH, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS
European journal of immunology 2013 Sep;43(9):2473-83
European journal of immunology 2013 Sep;43(9):2473-83
CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation.
Denoyer A, Godefroy D, Célérier I, Frugier J, Riancho L, Baudouin F, Rostène W, Baudouin C
Mucosal immunology 2012 Nov;5(6):702-11
Mucosal immunology 2012 Nov;5(6):702-11
Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor γδ are involved in bacterial clearance during Salmonella enterica serovar Typhimurium infection.
Li Z, Zhang C, Zhou Z, Zhang J, Zhang J, Tian Z
Infection and immunity 2012 Feb;80(2):565-74
Infection and immunity 2012 Feb;80(2):565-74
Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties.
Slavuljica I, Busche A, Babić M, Mitrović M, Gašparović I, Cekinović D, Markova Car E, Pernjak Pugel E, Ciković A, Lisnić VJ, Britt WJ, Koszinowski U, Messerle M, Krmpotić A, Jonjić S
The Journal of clinical investigation 2010 Dec;120(12):4532-45
The Journal of clinical investigation 2010 Dec;120(12):4532-45
Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells.
Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R
Blood 2009 Jun 11;113(24):6120-7
Blood 2009 Jun 11;113(24):6120-7
Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D.
Takada A, Yoshida S, Kajikawa M, Miyatake Y, Tomaru U, Sakai M, Chiba H, Maenaka K, Kohda D, Fugo K, Kasahara M
Journal of immunology (Baltimore, Md. : 1950) 2008 Feb 1;180(3):1678-85
Journal of immunology (Baltimore, Md. : 1950) 2008 Feb 1;180(3):1678-85
Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease.
Bahjat KS, Prell RA, Allen HE, Liu W, Lemmens EE, Leong ML, Portnoy DA, Dubensky TW Jr, Brockstedt DG, Giedlin MA
Journal of immunology (Baltimore, Md. : 1950) 2007 Dec 1;179(11):7376-84
Journal of immunology (Baltimore, Md. : 1950) 2007 Dec 1;179(11):7376-84
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