Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10582-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10582-1-AP, RRID:AB_2236833
- Product name
- PELO antibody
- Antibody type
- Polyclonal
- Description
- PELO antibody (Cat. #10582-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A role for the ribosome-associated complex in activation of the IRE1 branch of UPR.
Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology.
XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence.
Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation.
Wu IH, Yoon JS, Yang Q, Liu Y, Skach W, Thomas P
Cell reports 2021 Jun 8;35(10):109217
Cell reports 2021 Jun 8;35(10):109217
Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology.
Terrey M, Adamson SI, Chuang JH, Ackerman SL
eLife 2021 Apr 26;10
eLife 2021 Apr 26;10
XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence.
Hou S, Qu D, Li Y, Zhu B, Liang D, Wei X, Tang W, Zhang Q, Hao J, Guo W, Wang W, Zhao S, Wang Q, Azam S, Khan M, Zhao H, Zhang L, Lei H
Nucleic acids research 2019 Sep 5;47(15):8239-8254
Nucleic acids research 2019 Sep 5;47(15):8239-8254
Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation.
O'Connell AE, Gerashchenko MV, O'Donohue MF, Rosen SM, Huntzinger E, Gleeson D, Galli A, Ryder E, Cao S, Murphy Q, Kazerounian S, Morton SU, Schmitz-Abe K, Gladyshev VN, Gleizes PE, Séraphin B, Agrawal PB
PLoS genetics 2019 Feb;15(2):e1007917
PLoS genetics 2019 Feb;15(2):e1007917
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SKOV-3 cells were subjected to SDS PAGE followed by western blot with 10582-1-AP(PELO antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 10582-1-AP(PELO antibody) at dilution of 1:100 (under 25x lens)
- Sample type
- tissue