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Cell line expression
Protein structure
TJP3
Tight junction protein 3ZO-3
The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]
Top validated antibodies |
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| Invitrogen Antibodies |  36-4000 |
5 references | Polyclonal |
WB
EL
ICC
IP
IHC
OA
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| LSBio | LS-C354927 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Atlas Antibodies | HPA053337 |
Polyclonal |
ICC
IHC
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| Proteintech Group | 22116-1-AP |
1 references | Polyclonal |
WB
EL
|
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| antibodies-online | ABIN955227 |
3 references | Polyclonal |
WB
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