BS3806

antibody from Bioworld Technology, Inc
Targeting: APBA3 mint3, X11L2
Provider product page for BS3806
Western blot
Immunohistochemistry

Antibody data

Product number
BS3806 - Provider product page
Provider
Bioworld Technology, Inc
Product name
X11ÎÛ (R401) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 371-420 of Human X11ÎÛ.
Description
Amyloid ÉÇ precursor protein (ÉÇ APP) is a major constituent of the amyloid deposits in patients with Alzheimer£ªs disease. The amyloid ÉÇ precursor is known to interact with several proteins, including the G heterotrimetric protein, APP-BP1, and X11. The neuronal, transmembrane protein X11 is known to bind to the amyloid ÉÇ precurser protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular ÉÇ APP and slowing ÉÇ APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of ÉÇ APP. Multiple splice varitents of X11 have been identified, including X11 Ï«, ÉÇ and ÎÛ (also known as Mint 1, 2 and 3, respectively).
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
APBA3 protein structure - BS3806 shown in red.