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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 10171-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10171-1-AP, RRID:AB_10644158
- Product name
- Beta Arrestin 2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Beta Arrestin 2 antibody (Cat. #10171-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors.
Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy.
Bioactive peptide apelin rescues acute kidney injury by protecting the function of renal tubular mitochondria.
Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes.
Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation.
BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells.
β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.
β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation.
Lin JY, Yang Z, Yang C, Du JX, Yang F, Cheng J, Pan W, Zhang SJ, Yan X, Wang J, Wang J, Tie L, Yu X, Chen X, Sun JP
The Journal of biological chemistry 2021 Oct;297(4):101160
The Journal of biological chemistry 2021 Oct;297(4):101160
Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy.
Wei TT, Yang LT, Guo F, Tao SB, Cheng L, Huang RS, Ma L, Fu P
Acta pharmacologica Sinica 2021 Feb;42(2):252-263
Acta pharmacologica Sinica 2021 Feb;42(2):252-263
Bioactive peptide apelin rescues acute kidney injury by protecting the function of renal tubular mitochondria.
Guan YM, Diao ZL, Huang HD, Zheng JF, Zhang QD, Wang LY, Liu WH
Amino acids 2021 Aug;53(8):1229-1240
Amino acids 2021 Aug;53(8):1229-1240
Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes.
Ma K, Ding X, Song Q, Han Z, Yao H, Ding J, Hu G
Neuropharmacology 2020 Jul;171:108084
Neuropharmacology 2020 Jul;171:108084
Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation.
Wu Y, Hu Y, Wang B, Li S, Ma C, Liu X, Moynagh PN, Zhou J, Yang S
Molecular cell 2020 Apr 2;78(1):42-56.e6
Molecular cell 2020 Apr 2;78(1):42-56.e6
BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.
Ye F, Nager AR, Nachury MV
The Journal of cell biology 2018 May 7;217(5):1847-1868
The Journal of cell biology 2018 May 7;217(5):1847-1868
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells.
Liu YQ, Jia MQ, Xie ZH, Liu XF, Hui-Yang, Zheng XL, Yuan HQ, Bi JZ
Scientific reports 2017 Jun 13;7(1):3446
Scientific reports 2017 Jun 13;7(1):3446
β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.
Liu J, Li QX, Wang XJ, Zhang C, Duan YQ, Wang ZY, Zhang Y, Yu X, Li NJ, Sun JP, Yi F
Cell death & disease 2016 Apr 7;7:e2183
Cell death & disease 2016 Apr 7;7:e2183
β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation.
Seitz K, Dürsch V, Harnoš J, Bryja V, Gentzel M, Schambony A
PloS one 2014;9(1):e87132
PloS one 2014;9(1):e87132
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- RAW264.7 cells were subjected to SDS PAGE followed by western blot with 10171-1-AP(Beta Arrestin 2 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human spleen using 10171-1-AP(Beta Arrestin 2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human spleen using 10171-1-AP(Beta Arrestin 2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
