Antibody data

Product number
BS5700 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DNA pol š÷ 2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 144-189 of Human DNA pol š÷ 2.
Description
DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. Exonucleases involved in these processes include DNA polymerases, including DNA pol Ñ´ and š÷. DNA pol Ñ´ consists of two subunits-p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50. DNA pol Ñ´ can be regulated by cell cycle proteins. DNA pol š÷ is a multiple subunit enzyme, the catalytic subunit of which is encoded by the POL2 gene. The exact reactions catalyzed by DNA pol Ñ´ and š÷ on leading and lagging strands have not yet been elucidated.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
POLE2 protein structure - BS5700 shown in red.