313804

antibody from BioLegend

Targeting: IL18R1 CD218a, IL-1Rrp, IL1RRP

Western blot

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: 313804 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#313804, RRID:AB_345312
Product name: Purified anti-human CD218a (IL-18R)
Antibody type: Monoclonal
Antigen: Human NK cell line NK0 constitutively expressing IL-18 receptors
Description: IL-18 receptor is composed of an α and a β subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor α chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor α chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

IL18R1 protein structure - 313804 shown in red.