ALX-BC-6010-S-L005

antibody from Enzo Life Sciences

Targeting: TPO TPX

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ALX-BC-6010-S-L005

Provider

Enzo Life Sciences

Product name

Thyroid Peroxidase (human) monoclonal antibody (TPO 47)

Antibody type

Monoclonal

Antigen

Purified from natural sources

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

TPO 47

Vial size

5 ml

Storage

+4°C

References

Submitted references

Thyroid peroxidase forms thionamide-sensitive homodimers: relevance for immunomodulation of thyroid autoimmunity.

McDonald DO, Pearce SH
Journal of molecular medicine (Berlin, Germany) 2009 Oct;87(10):971-80

---

BRAFV600E mutation, but not RET/PTC rearrangements, is correlated with a lower expression of both thyroperoxidase and sodium iodide symporter genes in papillary thyroid cancer.

Romei C, Ciampi R, Faviana P, Agate L, Molinaro E, Bottici V, Basolo F, Miccoli P, Pacini F, Pinchera A, Elisei R
Endocrine-related cancer 2008 Jun;15(2):511-20

---

Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.

Landriscina M, Fabiano A, Altamura S, Bagalà C, Piscazzi A, Cassano A, Spadafora C, Giorgino F, Barone C, Cignarelli M
The Journal of clinical endocrinology and metabolism 2005 Oct;90(10):5663-71

---

Type I interferons modulate the expression of thyroid peroxidase, sodium/iodide symporter, and thyroglobulin genes in primary human thyrocyte cultures.

Caraccio N, Giannini R, Cuccato S, Faviana P, Berti P, Galleri D, Dardano A, Basolo F, Ferrannini E, Monzani F
The Journal of clinical endocrinology and metabolism 2005 Feb;90(2):1156-62

---

Molecular model, calcium sensitivity, and disease specificity of a conformational thyroperoxidase B-cell epitope.

Estienne V, Blanchet C, Niccoli-Sire P, Duthoit C, Durand-Gorde JM, Geourjon C, Baty D, Carayon P, Ruf J
The Journal of biological chemistry 1999 Dec 10;274(50):35313-7

---

A conformational B-cell epitope on the C-terminal end of the extracellular part of human thyroid peroxidase.

Estienne V, Duthoit C, Vinet L, Durand-Gorde JM, Carayon P, Ruf J
The Journal of biological chemistry 1998 Apr 3;273(14):8056-62

---

[Malignancy markers in the cytodiagnosis of thyroid nodules. Thyroid peroxidase].

de Micco C, Zoro P, Henry JF
Annales de pathologie 1994;14(6):378-83

---

Current evaluation of thyroid nodules.

Gharib H
Trends in endocrinology and metabolism: TEM 1994 Nov;5(9):365-9

---

Thyroid peroxidase immunodetection as a tool to assist diagnosis of thyroid nodules on fine-needle aspiration biopsy.

De Micco C, Zoro P, Garcia S, Skoog L, Tani EM, Carayon P, Henry JF
European journal of endocrinology / European Federation of Endocrine Societies 1994 Nov;131(5):474-9

---

Thyroperoxidase immunodetection for the diagnosis of malignancy on fine-needle aspiration of thyroid nodules.

Henry JF, Denizot A, Porcelli A, Villafane M, Zoro P, Garcia S, De Micco C
World journal of surgery 1994 Jul-Aug;18(4):529-34

---

Fine-needle aspiration of thyroid follicular neoplasm: diagnostic use of thyroid peroxidase immunocytochemistry with monoclonal antibody 47.

De Micco C, Vasko V, Garcia S, Zoro P, Denizot A, Henry JF
Surgery 1994 Dec;116(6):1031-5

---

Immunohistochemical study of thyroid peroxidase in normal, hyperplastic, and neoplastic human thyroid tissues.

De Micco C, Ruf J, Chrestian MA, Gros N, Henry JF, Carayon P
Cancer 1991 Jun 15;67(12):3036-41

---

Relationship between immunological structure and biochemical properties of human thyroid peroxidase.

Ruf J, Toubert ME, Czarnocka B, Durand-Gorde JM, Ferrand M, Carayon P
Endocrinology 1989 Sep;125(3):1211-8