Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS8454 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Histone H4 (Mono Methyl R3) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide conjugated to KLH derived from within residues 1-100 of Human Histone H4, Mono-methylated at R3.
- Description
- Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of extracts of HeLa cell line and H4 protein expressed in E.coli., using Histone H4 (Mono-Methyl R3) antibody.