DMAB9471

antibody from Creative Diagnostics

Targeting: OTOF DFNB6, DFNB9, FER1L2

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

DMAB9471

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMAB9471, RRID:AB_2393015

Product name

Anti-Otoferlin Monoclonal antibody, clone HCS-1

Antibody type

Monoclonal

Description

Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has 3 C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has 6 C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multiple isoforms have been found for this gene.

Reactivity

Chicken/Avian

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

HCS-1

Vial size

1 ea

Storage

-20 °C, Avoid freeze / thaw cycles