Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN251021 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DEAH (Asp-Glu-Ala-His) Box Polypeptide 33 (DHX33) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice.
The DHX33 RNA Helicase Promotes mRNA Translation Initiation.
The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.
The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome.
Identification of DHX33 as a mediator of rRNA synthesis and cell growth.
Fraile JM, Campos-Iglesias D, Rodríguez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Martín-Subero JI, Freije JMP, López-Otín C
The Journal of biological chemistry 2018 Feb 9;293(6):2183-2194
The Journal of biological chemistry 2018 Feb 9;293(6):2183-2194
The DHX33 RNA Helicase Promotes mRNA Translation Initiation.
Zhang Y, You J, Wang X, Weber J
Molecular and cellular biology 2015 Sep 1;35(17):2918-31
Molecular and cellular biology 2015 Sep 1;35(17):2918-31
The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation.
Weng L, Mitoma H, Trichot C, Bao M, Liu Y, Zhang Z, Liu YJ
Journal of immunology (Baltimore, Md. : 1950) 2014 Oct 1;193(7):3676-82
Journal of immunology (Baltimore, Md. : 1950) 2014 Oct 1;193(7):3676-82
The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome.
Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, Liu YJ
Immunity 2013 Jul 25;39(1):123-35
Immunity 2013 Jul 25;39(1):123-35
Identification of DHX33 as a mediator of rRNA synthesis and cell growth.
Zhang Y, Forys JT, Miceli AP, Gwinn AS, Weber JD
Molecular and cellular biology 2011 Dec;31(23):4676-91
Molecular and cellular biology 2011 Dec;31(23):4676-91
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB