Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 13578-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13578-1-AP, RRID:AB_2220174
- Product name
- ABCG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ABCG1 antibody (Cat. #13578-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.
Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages.
Expression of the circular RNAs in astaxanthin promotes cholesterol efflux from THP-1 cells based on RNA-seq.
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells.
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
The circFASN/miR-33a pathway participates in tacrolimus-induced dysregulation of hepatic triglyceride homeostasis.
Regulation mechanism of silkworm pupa oil PUFAs on cholesterol metabolism in hepatic cell L-02.
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Food with calorie restriction reduces the development of atherosclerosis in apoE-deficient mice.
Thioredoxin-1 promotes macrophage reverse cholesterol transport and protects liver from steatosis.
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Metformin ameliorates Ox-LDL-induced foam cell formation in raw264.7 cells by promoting ABCG-1 mediated cholesterol efflux.
ALDH2 deficiency inhibits Ox-LDL induced foam cell formation via suppressing CD36 expression.
Early Presymptomatic Changes in the Proteome of Mitochondria-Associated Membrane in the APP/PS1 Mouse Model of Alzheimer's Disease.
Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.
25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism.
MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition.
Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages.
Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells.
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.
ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose.
Liao X, Zhang Y, Xu B, Ali A, Liu X, Jia Q
Journal of Cancer 2021;12(20):6071-6080
Journal of Cancer 2021;12(20):6071-6080
Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages.
Mota AC, Dominguez M, Weigert A, Snodgrass RG, Namgaladze D, Brüne B
Frontiers in immunology 2021;12:637778
Frontiers in immunology 2021;12:637778
Expression of the circular RNAs in astaxanthin promotes cholesterol efflux from THP-1 cells based on RNA-seq.
Liu J, Wei Y, Lin Y, Zhang P, Zhang Z, Huang H, Wu H, Zou T
Genes & nutrition 2021 Aug 28;16(1):13
Genes & nutrition 2021 Aug 28;16(1):13
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638
British journal of pharmacology 2021 Apr;178(7):1620-1638
ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells.
Xue J, Fan J, Li Y, Wu W, Yan Q, Zheng Q
Analytical cellular pathology (Amsterdam) 2020;2020:2095645
Analytical cellular pathology (Amsterdam) 2020;2020:2095645
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.
Matsuda J, Takahashi A, Takabatake Y, Sakai S, Minami S, Yamamoto T, Fujimura R, Namba-Hamano T, Yonishi H, Nakamura J, Kimura T, Kaimori JY, Matsui I, Takahashi M, Nakao M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Yanagita M, Yoshimori T, Isaka Y
Autophagy 2020 Oct;16(10):1889-1904
Autophagy 2020 Oct;16(10):1889-1904
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
Zhang XW, Sui Y, Liu XX, Fu CY, Qiao YH, Liu WJ, Li ZZ, Li XQ, Cao W
International journal of biological macromolecules 2020 Oct 15;161:1346-1357
International journal of biological macromolecules 2020 Oct 15;161:1346-1357
The circFASN/miR-33a pathway participates in tacrolimus-induced dysregulation of hepatic triglyceride homeostasis.
Zhang C, Chen K, Wei R, Fan G, Cai X, Xu L, Cen B, Wang J, Xie H, Zheng S, Xu X
Signal transduction and targeted therapy 2020 Mar 27;5(1):23
Signal transduction and targeted therapy 2020 Mar 27;5(1):23
Regulation mechanism of silkworm pupa oil PUFAs on cholesterol metabolism in hepatic cell L-02.
Luo Y, Wang L, Lv Y, Wu X, Hou C, Li J
Journal of the science of food and agriculture 2020 Mar 15;100(4):1418-1425
Journal of the science of food and agriculture 2020 Mar 15;100(4):1418-1425
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31
BMC cancer 2020 Jan 13;20(1):31
Food with calorie restriction reduces the development of atherosclerosis in apoE-deficient mice.
Yang J, Zeng P, Liu L, Yu M, Su J, Yan Y, Ma J, Hu W, Yang X, Han J, Duan Y, Chen Y
Biochemical and biophysical research communications 2020 Apr 2;524(2):439-445
Biochemical and biophysical research communications 2020 Apr 2;524(2):439-445
Thioredoxin-1 promotes macrophage reverse cholesterol transport and protects liver from steatosis.
Wang X, Zhao H, Yan W, Liu Y, Yin T, Wang S, Fan M, Li C, Zhang L, Tao L
Biochemical and biophysical research communications 2019 Sep 3;516(4):1103-1109
Biochemical and biophysical research communications 2019 Sep 3;516(4):1103-1109
Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.
Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, Shan Q, Liu S
Environment international 2019 Jul;128:146-157
Environment international 2019 Jul;128:146-157
Metformin ameliorates Ox-LDL-induced foam cell formation in raw264.7 cells by promoting ABCG-1 mediated cholesterol efflux.
He X, Chen X, Wang L, Wang W, Liang Q, Yi L, Wang Y, Gao Q
Life sciences 2019 Jan 1;216:67-74
Life sciences 2019 Jan 1;216:67-74
ALDH2 deficiency inhibits Ox-LDL induced foam cell formation via suppressing CD36 expression.
Wei S, Zhang L, Bailu Wang, Zhao Y, Dong Q, Pan C, Li C, He D, Yuan Q, Xu F, Chen Y
Biochemical and biophysical research communications 2019 Apr 23;512(1):41-48
Biochemical and biophysical research communications 2019 Apr 23;512(1):41-48
Early Presymptomatic Changes in the Proteome of Mitochondria-Associated Membrane in the APP/PS1 Mouse Model of Alzheimer's Disease.
Völgyi K, Badics K, Sialana FJ, Gulyássy P, Udvari EB, Kis V, Drahos L, Lubec G, Kékesi KA, Juhász G
Molecular neurobiology 2018 Oct;55(10):7839-7857
Molecular neurobiology 2018 Oct;55(10):7839-7857
Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.
Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, Zhang X, Yang S, Sun L, Yu M, Yang J, Li X, Hu W, Miao RQ, Zhu Y, Li L, Han J, Chen Y, Duan Y
British journal of pharmacology 2018 May;175(9):1486-1503
British journal of pharmacology 2018 May;175(9):1486-1503
25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism.
Liu Y, Wei Z, Ma X, Yang X, Chen Y, Sun L, Ma C, Miao QR, Hajjar DP, Han J, Duan Y
Journal of lipid research 2018 Mar;59(3):439-451
Journal of lipid research 2018 Mar;59(3):439-451
MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition.
Zhang L, Chen Y, Yang X, Yang J, Cao X, Li X, Li L, Miao QR, Hajjar DP, Duan Y, Han J
Biochimica et biophysica acta 2016 Sep;1861(9 Pt A):1180-1191
Biochimica et biophysica acta 2016 Sep;1861(9 Pt A):1180-1191
Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages.
Liu F, Wang Y, Xu J, Liu F, Hu R, Deng H
Archives of medical science : AMS 2016 Oct 1;12(5):959-967
Archives of medical science : AMS 2016 Oct 1;12(5):959-967
Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells.
Hao S, Ji J, Zhao H, Shang L, Wu J, Li H, Qiao T, Li K
Molecules (Basel, Switzerland) 2015 Dec 1;20(12):21287-97
Molecules (Basel, Switzerland) 2015 Dec 1;20(12):21287-97
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Xue J, Wei J, Dong X, Zhu C, Li Y, Song A, Liu Z
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.
Zhang L, Jiang M, Shui Y, Chen Y, Wang Q, Hu W, Ma X, Li X, Liu X, Cao X, Liu M, Duan Y, Han J
Biochimica et biophysica acta 2013 Jun;1831(6):1134-45
Biochimica et biophysica acta 2013 Jun;1831(6):1134-45
ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose.
Xue J, Wang C, Zhu C, Li Y
Diabetes research and clinical practice 2013 Jul;101(1):72-80
Diabetes research and clinical practice 2013 Jul;101(1):72-80
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ABCG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ABCG1. This antibody recognizes human,mouse,rat antigen. The ABCG1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 13578-1-AP(ABCG1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 13578-1-AP(ABCG1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue