AMM04288G

antibody from Leading Biology

Targeting: UBR1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM04288G

Provider

Leading Biology

Product name

UBR1 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2F5

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.