CABT-B12158

antibody from Creative Diagnostics

Targeting: MPL CD110, THPOR, TPOR

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12158

Provider

Creative Diagnostics

Product name

Human anti-Human MPL recombinant monoclonal antibody, clone SFB360 [PE]

Antibody type

Monoclonal

Description

It recognozes the CD110 antigen, a type I transmembrane protein and a member of the hematopoietin receptor family, which is also known as myeloproliferative leukemia protein (MPL) or thrombopoietin receptor (TPO-R). CD110 is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets. It serves as a receptor for thrombopoietin and CD110 deficiency leads to severe thrombocytopenia, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Additional information: It displays negligible binding to Fc receptors.

Reactivity

Human

Host

Human

Conjugate

Yellow dye

Isotype

IgG

Antibody clone number

SFB360

Vial size

for 100 tests

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.