Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL4186 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-ATP6V0C (aa 71-120) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010]
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 _g
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
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