PB9684

antibody from Boster Biological Technology
Targeting: APBB1 Fe65, RIR
Provider product page for PB9684
Western blot
Immunohistochemistry

Antibody data

Product number
PB9684 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-FE65/APBB1 Antibody Picoband™
Antibody type
Polyclonal
Description
Polyclonal antibody for FE65/APBB1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. FE65/APBB1 information: Molecular Weight: 77244 MW; Subcellular Localization: Cell membrane. Cytoplasm. Nucleus. Cell projection, growth cone . Nucleus speckle. Colocalizes with TSHZ3 in axonal growth cone (By similarity). In normal conditions, it mainly localizes to the cytoplasm, while a small fraction is tethered to the cell membrane via its interaction with APP. Following exposure to DNA damaging agents, it is released from cell membrane and translocates to the nucleus. Nuclear translocation is under the regulation of APP. Colocalizes with TSHZ3 in the nucleus. Colocalizes with NEK6 at the nuclear speckles. Phosphorylation at Ser-610 by SGK1 promotes its localization to the nucleus (By similarity); Tissue Specificity: Highly expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Vial size
100μg/vial
Concentration
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Handling
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
APBB1 protein structure - PB9684 shown in red.