Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN252333 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-XiAP Associated Factor 1 (XAF1) antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 0.1 mg
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.
Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer.
XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway.
Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, Gerald WL, Montironi R, Signoretti S, Loda M, Nardella C, Pandolfi PP
Nature genetics 2013 Jul;45(7):747-55
Nature genetics 2013 Jul;45(7):747-55
Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer.
Kempkensteffen C, Fritzsche FR, Johannsen M, Weikert S, Hinz S, Dietel M, Riener MO, Moch H, Jung K, Krause H, Miller K, Kristiansen G
BMC cancer 2009 Aug 8;9:276
BMC cancer 2009 Aug 8;9:276
XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway.
Straszewski-Chavez SL, Visintin IP, Karassina N, Los G, Liston P, Halaban R, Fadiel A, Mor G
The Journal of biological chemistry 2007 Apr 27;282(17):13059-72
The Journal of biological chemistry 2007 Apr 27;282(17):13059-72
Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.
Xia Y, Novak R, Lewis J, Duckett CS, Phillips AC
Molecular and cellular biochemistry 2006 Jun;286(1-2):67-76
Molecular and cellular biochemistry 2006 Jun;286(1-2):67-76
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
Wang X, Zhu C, Wang X, Hagberg H, Korhonen L, Sandberg M, Lindholm D, Blomgren K
Neurobiology of disease 2004 Jun;16(1):179-89
Neurobiology of disease 2004 Jun;16(1):179-89
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB