13389-1-AP

antibody from Proteintech Group

Targeting: PFKP PFK-C, PFKF

Provider product page for 13389-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [24]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [1]

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Product number: 13389-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13389-1-AP, RRID:AB_2252278
Product name: PFKP antibody
Antibody type: Polyclonal
Description: KD/KO validated PFKP antibody (Cat. #13389-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

PFKP protein structure - 13389-1-AP shown in red.

Submitted references Augmentation of scleral glycolysis promotes myopia through histone lactylation.

Lin X, Lei Y, Pan M, Hu C, Xie B, Wu W, Su J, Li Y, Tan Y, Wei X, Xue Z, Xu R, Di M, Deng H, Liu S, Yang X, Qu J, Chen W, Zhou X, Zhao F
Cell metabolism 2024 Mar 5;36(3):511-525.e7

Time of exercise differentially impacts bone growth in mice.

Yu S, Tang Q, Lu X, Chen G, Xie M, Yang J, Yin Y, Zheng W, Wang J, Han Y, Zhang L, Chen L
Nature metabolism 2024 Jun;6(6):1036-1052

Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.

Cheng Z, Huang H, Li M, Chen Y
iScience 2024 Jan 19;27(1):108645

Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling.

Cong Y, Cui X, Shi Y, Pan X, Huang K, Geng Z, Xu P, Ge L, Zhu J, Xu J, Jia X
Molecular and cellular biochemistry 2024 Feb 17;

Quercetin Impairs the Growth of Uveal Melanoma Cells by Interfering with Glucose Uptake and Metabolism.

Tura A, Herfs V, Maaßen T, Zuo H, Vardanyan S, Prasuhn M, Ranjbar M, Kakkassery V, Grisanti S
International journal of molecular sciences 2024 Apr 12;25(8)

PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer.

Wang Z, Wu S, Chen X, Liang J, Xue F, Cho WC, Bao J, Chen B, Ye M, Ma D, Zhu C, Zhu J, Shen J
Translational lung cancer research 2023 Nov 30;12(11):2294-2309

C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.

Tan J, Wang W, Liu X, Xu J, Che Y, Liu Y, Hu J, Hu L, Li J, Zhou Q
Communications biology 2023 Jun 5;6(1):606

TMT Labeling Reveals the Effects of Exercises on the Proteomic Characteristics of the Subcutaneous Adipose Tissue of Growing High-Fat-Diet-Fed Rats.

Song G, Chen J, Deng Y, Sun L, Yan Y
ACS omega 2023 Jul 4;8(26):23484-23500

Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.

Ai YL, Wang WJ, Liu FJ, Fang W, Chen HZ, Wu LZ, Hong X, Zhu Y, Zhang CX, Liu LY, Hong WB, Zhou B, Chen QT, Wu Q
Cell research 2023 Dec;33(12):904-922

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes.

Wu H, Kren BT, Lane AN, Cassel TA, Higashi RM, Fan TWM, Scaria GS, Shekels LL, Klein MA, Albrecht JH
The Journal of biological chemistry 2023 Dec;299(12):105407

Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis.

Xu L, Yang TY, Zhou YW, Wu MF, Shen J, Cheng JL, Liu QX, Cao SY, Wang JQ, Zhang L
Acta pharmacologica Sinica 2022 Feb;43(2):316-329

Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.

Jin X, Li X, Li L, Zhong B, Hong Y, Niu J, Li B
The Journal of biological chemistry 2022 Dec;298(12):102587

Combination of the Herbs Radix Rehmanniae and Cornus Officinalis Mitigated Testicular Damage From Diabetes Mellitus by Enhancing Glycolysis via the AGEs/RAGE/HIF-1α Axis.

Chen Y, Chen J, Shu A, Liu L, Wu Q, Wu J, Song S, Fan W, Zhu Y, Xu H, Sun J, Yang L
Frontiers in pharmacology 2021;12:678300

Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease.

Zhou Y, Wu M, Xu L, Cheng J, Shen J, Yang T, Zhang L
Frontiers in pharmacology 2021;12:640521

RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.

Li M, Chen X, Wang X, Wei X, Wang D, Liu X, Xu L, Batu W, Li Y, Guo B, Zhang L
Biochemical pharmacology 2021 Oct;192:114741

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m(6)A/PFKP/LDHB axis.

Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Ten Hoeve J, Sanchez GJ, Chen H, Chan LN, Chen CW, Ann D, Jiang L, Müschen M, Marcucci G, Plas DR, Li Z, Su R, Chen J
Molecular cell 2021 Mar 4;81(5):922-939.e9

Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells.

Shi W, Fu Y, Wang Y
Oncology letters 2021 Jul;22(1):527

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

Zhu M, Wang Q, Tian P, Cheng L, Sun Z, Hong Q, Lv P, Ji L, Liu Y, Tang QQ, Wen B
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165988

Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.

Zhang Y, Tang Y, Luo Y, Luo L, Shen F, Huang Z
Toxicology and applied pharmacology 2021 Aug 15;425:115606

The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cells.

Gao W, Huang M, Chen X, Chen J, Zou Z, Li L, Ji K, Nie Z, Yang B, Wei Z, Xu P, Jia J, Zhang Q, Shen H, Wang Q, Li K, Zhu L, Wang M, Ye S, Zeng S, Lin Y, Rong Z, Xu Y, Zhu P, Zhang H, Hao B, Liu Q
Cell death & disease 2021 Apr 15;12(4):408

Novel mitochondrion-targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1-mediating mitophagy in HCC.

Li M, Shao J, Guo Z, Jin C, Wang L, Wang F, Jia Y, Zhu Z, Zhang Z, Zhang F, Zheng S, Wang X
Journal of cellular and molecular medicine 2020 Mar;24(5):3091-3107

Ginsenoside Rh4 suppresses aerobic glycolysis and the expression of PD-L1 via targeting AKT in esophageal cancer.

Deng X, Zhao J, Qu L, Duan Z, Fu R, Zhu C, Fan D
Biochemical pharmacology 2020 Aug;178:114038

Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.

Gu Z, Zhang H, Guo X, Cao Y
The Journal of investigative dermatology 2020 Aug;140(8):1513-1523.e5

The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway.

Sun Z, Zhu M, Lv P, Cheng L, Wang Q, Tian P, Yan Z, Wen B
Stem cell reports 2018 Sep 11;11(3):741-755

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse heart tissue were subjected to SDS PAGE followed by western blot with 13389-1-AP(PFKP antibody) at dilution of 1:1500
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The PFKP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PFKP. This antibody recognizes human,mouse,rat antigen. The PFKP antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 13389-1-AP.pdf

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