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Protein structure
PIK3C2G
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gammaThe protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Affinity Biosciences |  DF10131 |
Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-99834 |
Polyclonal |
WB
ICC
IHC
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| Abnova Corporation | PAB3208 |
1 references | Polyclonal |
WB
IHC
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| LSBio | LS-C802391 |
Polyclonal |
WB
EL
ICC
IHC
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| NovoPro Bioscience Inc. | 136625 |
Polyclonal |
WB
EL
IHC
|
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