Antibody data

Product number
BS3302 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3302, RRID:AB_1662268
Product name
GCP4 (L225) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 197-243 of Human GCP4.
Description
The ÎÛ-Tubulin complex is composed of ÎÛ Tubulin and the ÎÛ-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. ÎÛ-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the ÎÛ-Tubulin complex. GCP4 (ÎÛ-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the ÎÛ-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TUBGCP4 protein structure - BS3302 shown in red.