Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx304988 - Provider product page
- Provider
- Abbexa
- Product name
- 26S Proteasome Regulatory Subunit 10B (PSMC6) Antibody (FITC)
- Antibody type
- Polyclonal
- Description
- 26S Proteasome Regulatory Subunit 10B (PSMC6) Antibody (FITC) is a Rabbit Polyclonal against 26S Proteasome Regulatory Subunit 10B (PSMC6) conjugated to FITC. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 µg
- Storage
- Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
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