orb149810

antibody from Biorbyt
Targeting: ATP7B WND
Provider product page for orb149810
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb149810 - Provider product page
Provider
Biorbyt
Product name
Copper Transporting ATPase 2 Antibody: Biotin
Antibody type
Monoclonal
Description
Mouse monoclonal to Copper Transporting ATPase 2 (Biotin). The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage..
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Biotin
Isotype
IgG
Antibody clone number
L62/29 (Formerly sold as S62-29)
Vial size
100 ug
Concentration
1 mg/ml
Storage
Conjugated antibodies should be stored according to the product label
ATP7B protein structure - orb149810 shown in red.