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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PA5-25338 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CRLS1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with mouse and rat based on sequence homology.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia.
Gianni' M, Goracci L, Schlaefli A, Di Veroli A, Kurosaki M, Guarrera L, Bolis M, Foglia M, Lupi M, Tschan MP, Cruciani G, Terao M, Garattini E
Cell death & disease 2022 Jan 10;13(1):30
Cell death & disease 2022 Jan 10;13(1):30
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis using a CRLS1 polyclonal antibody (Product # PA5-25338) in T47D cell lysates (35 µg per lane).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis in formalin-fixed, paraffin-embedded human skeletal muscle using a CRLS1 polyclonal antibody (Product # PA5-25338), followed by HRP-conjugated secondary antibody and DAB staining.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig. 8 ATRA effects on the expression of the genes belonging to the glycerophospholipid metabolism pathway in parental NB4, NB4-shCTRL, and NB4-shATG5 cells. A The effects exerted by ATRA on the genes belonging to the glycerophospholipid pathway in parental NB4 , NB4-shCTRL , and NB4-shATG5 cells were evaluated using the RNA-seq data generated from the three cell lines exposed to vehicle (DMSO) or ATRA (1 muM) for 48 h. The diagrams show the perturbations induced by ATRA on the expression of the indicated genes. The results presented in each box are expressed using the Log 2 of the ATRA-dependent fold-change values which we determined. The names of the genes whose expression is significantly increased by ATRA in the indicated cell-lines are written in red. The names of the genes whose expression is significantly decreased by ATRA in the indicated cell-lines are written in blue. When the indicated genes are significantly up-regulated (FDR > 0.05), the positive fold-change values are contained in a red box and are marked with an asterisk. When the indicated genes are significantly down-regulated (FDR > 0.05), the negative fold-change values are contained in a light blue box. B The column diagrams indicate the expression levels of the CRLS1 , LPCAT1 , and PGS1 mRNAs which were determined in three independent cultures of NB4-shCTRL and NB4-shATG5 cells, by PCR using specific Taqman Assays. The results are expressed as the Mean + S.D. ( N = 3) of the values determined. **Significa
