BS7454

antibody from Bioworld Technology, Inc
Targeting: GRPR BB2, BB2R
Provider product page for BS7454
Western blot
Immunohistochemistry

Antibody data

Product number
BS7454 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GRPR polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GRPR.
Description
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GRPR protein structure - BS7454 shown in red.