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LearnBS3804
antibody from Bioworld Technology, Inc
Targeting: AKR1C2
BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS3804 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- DD2 (Q60) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 50-100 of Human DD2.
- Description
- DD1 is also designated AKR1C1, DDH or DDH1, while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3Ï«-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), while DD4 also can be called AKR1C4, CD, CHDR or AKR1C6 (in rodents). DD1 and DD2 are 20Ï«-HSDs, whereas DD3 and DD4 are the 3Ï«- HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20Ï«- HSD catalyzes the reaction of Progesterone to the inactive form 20Ï«-hydroxyprogesterone.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of DD2 (Q60) pAb at 1:500 dilutionLane1:HepG2 cell lysateLane2:Mouse liver tissue lysateLane3:Rat liver tissue lysate
