Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11134-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11134-1-AP, RRID:AB_2289288
- Product name
- Aconitase 2 antibody
- Antibody type
- Polyclonal
- Description
- Aconitase 2 antibody (Cat. #11134-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Proteomic Profile of Sperm in Infertile Males Reveals Changes in Metabolic Pathways.
Bioenergetic functions in subpopulations of heart mitochondria are preserved in a non-obese type 2 diabetes rat model (Goto-Kakizaki).
The Symbiotic Relationship between the Neural Retina and Retinal Pigment Epithelium Is Supported by Utilizing Differential Metabolic Pathways.
Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity mediated by Lonp1/Aco2/Hsp75.
miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism.
Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts.
Altered Aconitase 2 Activity in Huntington's Disease Peripheral Blood Cells and Mouse Model Striatum.
A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Tumor Necrosis Factor-Associated Protein 1 (TRAP1) is Released from the Mitochondria Following 6-hydroxydopamine Treatment.
A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism.
Wang YP, Sharda A, Xu SN, van Gastel N, Man CH, Choi U, Leong WZ, Li X, Scadden DT
Cell metabolism 2021 May 4;33(5):1027-1041.e8
Cell metabolism 2021 May 4;33(5):1027-1041.e8
Proteomic Profile of Sperm in Infertile Males Reveals Changes in Metabolic Pathways.
Liang J, Zheng Y, Zeng W, Chen L, Yang S, Du P, Wang Y, Yu X, Zhang X
The protein journal 2021 Dec;40(6):929-939
The protein journal 2021 Dec;40(6):929-939
Bioenergetic functions in subpopulations of heart mitochondria are preserved in a non-obese type 2 diabetes rat model (Goto-Kakizaki).
Lai N, Kummitha CM, Loy F, Isola R, Hoppel CL
Scientific reports 2020 Mar 25;10(1):5444
Scientific reports 2020 Mar 25;10(1):5444
The Symbiotic Relationship between the Neural Retina and Retinal Pigment Epithelium Is Supported by Utilizing Differential Metabolic Pathways.
Sinha T, Naash MI, Al-Ubaidi MR
iScience 2020 Apr 24;23(4):101004
iScience 2020 Apr 24;23(4):101004
Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity mediated by Lonp1/Aco2/Hsp75.
Li C, Chen W, Zheng L, Zhang B, Yang X, Zhang Q, Wang N, Wang Y, Yang J, Sha J, Zhou Z, Li X, Li Y, Shen XL
Toxicon : official journal of the International Society on Toxinology 2019 Oct;168:141-146
Toxicon : official journal of the International Society on Toxinology 2019 Oct;168:141-146
miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism.
Muys BR, Sousa JF, Plaça JR, de Araújo LF, Sarshad AA, Anastasakis DG, Wang X, Li XL, de Molfetta GA, Ramão A, Lal A, Vidal DO, Hafner M, Silva WA
Cancer research 2019 Jul 1;79(13):3294-3305
Cancer research 2019 Jul 1;79(13):3294-3305
Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts.
Li H, Zhao H, Hao S, Shang L, Wu J, Song C, Meyron-Holtz EG, Qiao T, Li K
Scientific reports 2018 Mar 23;8(1):5118
Scientific reports 2018 Mar 23;8(1):5118
Altered Aconitase 2 Activity in Huntington's Disease Peripheral Blood Cells and Mouse Model Striatum.
Chen CM, Wu YR, Chang KH
International journal of molecular sciences 2017 Nov 21;18(11)
International journal of molecular sciences 2017 Nov 21;18(11)
A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Pryde KR, Taanman JW, Schapira AH
Cell reports 2016 Dec 6;17(10):2522-2531
Cell reports 2016 Dec 6;17(10):2522-2531
Tumor Necrosis Factor-Associated Protein 1 (TRAP1) is Released from the Mitochondria Following 6-hydroxydopamine Treatment.
Shin DI, Oh YJ
Experimental neurobiology 2014 Mar;23(1):65-76
Experimental neurobiology 2014 Mar;23(1):65-76
A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism.
Cai Z, Zhao JS, Li JJ, Peng DN, Wang XY, Chen TL, Qiu YP, Chen PP, Li WJ, Xu LY, Li EM, Tam JP, Qi RZ, Jia W, Xie D
Molecular & cellular proteomics : MCP 2010 Dec;9(12):2617-28
Molecular & cellular proteomics : MCP 2010 Dec;9(12):2617-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11134-1-AP(ACO2 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Aconitase 2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Aconitase 2. This antibody recognizes human,mouse,rat antigen. The Aconitase 2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.