BS4068

antibody from Bioworld Technology, Inc
Targeting: EFNB2 EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228
Provider product page for BS4068
Western blot
Immunohistochemistry

Antibody data

Product number
BS4068 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Ephrin B1/2 (phospho Y330)
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Ephrin-B2 around the phosphorylation site of Tyrosine 330.
Description
Ephrin-B proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EFNB2 protein structure - BS4068 shown in red.