AGTO-G074A

antibody from Creative Biolabs

Targeting: BDP1 HSA238520, KIAA1241, KIAA1689, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR

No application information provided.

Antibody Data

Product number

AGTO-G074A

Provider

Creative Biolabs

Product name

transferrin-ABR immunotoxin

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the transferrin to Abrin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the abrin is subsequently engulfed and enters the inner parts of the cell where it reacts with a ribosomal subunit. It interferes with the normal protein synthesis process of the cell and then inhibits cell protein synthesis. It was designed for treatment of myelogenous leukemia.

Reactivity

Human

Host

Human