CABT-B11236

antibody from Creative Diagnostics

Targeting: RNF170 ADSA, DKFZP564A022, SNAX1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B11236

Provider

Creative Diagnostics

Product name

Mouse anti-Human RNF170 monoclonal antibody, clone 3E7

Antibody type

Monoclonal

Description

This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3.00E+07

Vial size

100 _g

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.