BS8338

antibody from Bioworld Technology, Inc
Targeting: NEK3 HSPK36, MGC29949
Provider product page for BS8338
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8338 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NEK3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NEK3.
Description
NIMA was originally shown in Aspergillus nidulans to be necessary for entry into mitosis. NIMA-related mammalian proteins have since been identified as Nek1, Nek2, Nek3 and Nek4 (also designated STK2 or NRK2). High expression of Nek1 is seen in male and female germ cell lines of mouse. Nek2 is the closest known mammalian relative to NIMA. Like NIMA, Nek2 expression peaks at the G2 to M phase transition. Nek3 is a predominantly cytoplasmic enzyme that was detectable in all organs studied. Levels of Nek3 seem to remain unchanged throughout the cell cycle, but appear to be elevated in G0-arrested, quiescent fibroblasts. In developing testicular germ cells, differential patterns of expression were seen for Nek1, Nek2 and Nek4, indicating possible overlapping, but non-identical functions.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NEK3 protein structure - BS8338 shown in red.