BS7892

antibody from Bioworld Technology, Inc
Targeting: RHOT1 ARHT1, FLJ11040, MIRO-1, MIRO1
Provider product page for BS7892
Western blot
Immunohistochemistry

Antibody data

Product number
BS7892 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RHOT1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human RHOT1.
Description
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho T1 (ras homolog gene family, member T1), also known as ARHT1 or MIRO-1 (mitochondrial Rho GTPase 1), is an evolutionarily conserved member of the mitochondrial Rho GTPase family of proteins. Localizing to the mitochondrion, Rho T1 is widely expressed with predominant expression in skeletal muscle and heart. Rho T1 is a single-pass type IV membrane protein with two EF-hand domains and two GTPase domains (one at the N-terminus and one at the C-terminus). It is believed to play a role in the regulation of mitochondrial homeostasis and specifically binds to the kinesin-interacting proteins GRIF-1 and OIP106. Mutations in the gene encoding Rho T1 result in aggregation of the mitochondria. This suggests a potential role for Rho T1 in mitochondrial trafficking.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RHOT1 protein structure - BS7892 shown in red.