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- References [124]
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- Product number
- 10427-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10427-2-AP, RRID:AB_2069033
- Product name
- Calnexin antibody
- Antibody type
- Polyclonal
- Description
- Calnexin antibody (Cat. #10427-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.
STING regulates BCR signaling in normal and malignant B cells.
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.
Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8+ T cell response in tumor.
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.
The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.
Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.
Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.
USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.
Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Microglia as modulators of exosomal alpha-synuclein transmission.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.
Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.
Carrascal M, Areny-Balagueró A, de-Madaria E, Cárdenas-Jaén K, García-Rayado G, Rivera R, Martin Mateos RM, Pascual-Moreno I, Gironella M, Abian J, Closa D
The Journal of pathology 2022 Jan;256(1):83-92
The Journal of pathology 2022 Jan;256(1):83-92
The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
Shi J, Li Z, Xu R, Zhang J, Zhou Q, Gao R, Lu H, Lan Y, Zhao K, He H, Gao F, He W
Journal of virology 2022 Jan 12;96(1):e0169521
Journal of virology 2022 Jan 12;96(1):e0169521
Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
Li S, Liao Z, Luo R, Song Y, Wang K, Feng X, Ou Y, Wu X, Zhang Y, Gao Y, Yin H, Yang C
Frontiers in cell and developmental biology 2021;9:672847
Frontiers in cell and developmental biology 2021;9:672847
MiR-3064 in Epicardial Adipose-Derived Exosomes Targets Neuronatin to Regulate Adipogenic Differentiation of Epicardial Adipose Stem Cells.
Yang W, Tu H, Tang K, Huang H, Ou S, Wu J
Frontiers in cardiovascular medicine 2021;8:709079
Frontiers in cardiovascular medicine 2021;8:709079
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity.
Guo S, Gu J, Ma J, Xu R, Wu Q, Meng L, Liu H, Li L, Xu Y
Theranostics 2021;11(17):8379-8395
Theranostics 2021;11(17):8379-8395
SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.
Han L, Zhuang MW, Deng J, Zheng Y, Zhang J, Nan ML, Zhang XJ, Gao C, Wang PH
Journal of medical virology 2021 Sep;93(9):5376-5389
Journal of medical virology 2021 Sep;93(9):5376-5389
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Huang J, Yu M, Yin W, Liang B, Li A, Li J, Li X, Zhao S, Liu F
Bioactive materials 2021 Sep;6(9):2841-2853
Bioactive materials 2021 Sep;6(9):2841-2853
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267
Molecular neurobiology 2021 Sep;58(9):4251-4267
Neuronal Exosomes Secreted under Oxygen-Glucose Deprivation/Reperfusion Presenting Differentially Expressed miRNAs and Affecting Neuronal Survival and Neurite Outgrowth.
Chiang CS, Fu SJ, Hsu CL, Jeng CJ, Tang CY, Huang YS, Tang SC
Neuromolecular medicine 2021 Sep;23(3):404-415
Neuromolecular medicine 2021 Sep;23(3):404-415
Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
Jia W, Zou X, Xu Z, Bai L, Shan A, Li Y, Shi J, Yang F, Ding C, Narimatsu H, Zhang Y
Glycobiology 2021 Sep 9;31(8):947-958
Glycobiology 2021 Sep 9;31(8):947-958
Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation.
Xie Y, Liu G, Zang X, Hu Q, Zhou C, Li Y, Liu D, Hong L
Cells 2021 Sep 3;10(9)
Cells 2021 Sep 3;10(9)
Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence.
Zheng H, Liang X, Han Q, Shao Z, Zhang Y, Shi L, Hong Y, Li W, Mai C, Mo Q, Fu Q, Ma X, Lin F, Li M, Hu B, Li X, Zhang Y
Journal of nanobiotechnology 2021 Oct 21;19(1):332
Journal of nanobiotechnology 2021 Oct 21;19(1):332
Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.
Rimal S, Li Y, Vartak R, Geng J, Tantray I, Li S, Huh S, Vogel H, Glabe C, Grinberg LT, Spina S, Seeley WW, Guo S, Lu B
Acta neuropathologica communications 2021 Oct 18;9(1):169
Acta neuropathologica communications 2021 Oct 18;9(1):169
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation.
Zhang X, Qu YY, Liu L, Qiao YN, Geng HR, Lin Y, Xu W, Cao J, Zhao JY
Cell reports 2021 Oct 12;37(2):109821
Cell reports 2021 Oct 12;37(2):109821
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Cheng L, Yu P, Li F, Jiang X, Jiao X, Shen Y, Lai X
Human cell 2021 Nov;34(6):1697-1708
Human cell 2021 Nov;34(6):1697-1708
Comparison of MicroRNA Profiles in Extracellular Vesicles from Small and Large Goat Follicular Fluid.
Ding Q, Jin M, Kalds P, Meng C, Wang H, Zhong J, Wang X, Chen Y
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
Animals : an open access journal from MDPI 2021 Nov 8;11(11)
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2021 Nov 6;:1-14
Autophagy 2021 Nov 6;:1-14
hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression.
Li C, Qin F, Wang W, Ni Y, Gao M, Guo M, Sun G
International journal of molecular sciences 2021 Nov 28;22(23)
International journal of molecular sciences 2021 Nov 28;22(23)
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.
Mak HY, Ouyang Q, Tumanov S, Xu J, Rong P, Dong F, Lam SM, Wang X, Lukmantara I, Du X, Gao M, Brown AJ, Gong X, Shui G, Stocker R, Huang X, Chen S, Yang H
Nature communications 2021 Nov 25;12(1):6877
Nature communications 2021 Nov 25;12(1):6877
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
SMYD3-PARP16 axis accelerates unfolded protein response and mediates neointima formation.
Long F, Yang D, Wang J, Wang Q, Ni T, Wei G, Zhu Y, Liu X
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
Acta pharmaceutica Sinica. B 2021 May;11(5):1261-1273
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
Zhang J, Huang F, Xia B, Yuan Y, Yu F, Wang G, Chen Q, Wang Q, Li Y, Li R, Song Z, Pan T, Chen J, Lu G, Zhang H
Signal transduction and targeted therapy 2021 May 12;6(1):189
Signal transduction and targeted therapy 2021 May 12;6(1):189
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
Zhang Y, Chen Y, Li Y, Huang F, Luo B, Yuan Y, Xia B, Ma X, Yang T, Yu F, Liu J, Liu B, Song Z, Chen J, Yan S, Wu L, Pan T, Zhang X, Li R, Huang W, He X, Xiao F, Zhang J, Zhang H
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 8;118(23)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 8;118(23)
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Takahashi K, Niki T, Ogawa E, Fumika K, Nishioka Y, Sawa M, Arai H, Mukai K, Taguchi T
Scientific reports 2021 Jun 7;11(1):11996
Scientific reports 2021 Jun 7;11(1):11996
Identification of exosome miRNAs in bronchial epithelial cells after PM2.5 chronic exposure.
Wang Y, Zhong Y, Sun K, Fan Y, Liao J, Wang G
Ecotoxicology and environmental safety 2021 Jun 1;215:112127
Ecotoxicology and environmental safety 2021 Jun 1;215:112127
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer.
Zhang J, Fu B, Li M, Mi S
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2004750
Small (Weinheim an der Bergstrasse, Germany) 2021 Jan;17(4):e2004750
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
Small RNA-seq analysis of extracellular vesicles from porcine uterine flushing fluids during peri-implantation.
Hua R, Wang Y, Lian W, Li W, Xi Y, Xue S, Kang T, Lei M
Gene 2021 Jan 15;766:145117
Gene 2021 Jan 15;766:145117
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
GBA Mutations Influence the Release and Pathological Effects of Small Extracellular Vesicles from Fibroblasts of Patients with Parkinson's Disease.
Cerri S, Ghezzi C, Ongari G, Croce S, Avenali M, Zangaglia R, Di Monte DA, Valente EM, Blandini F
International journal of molecular sciences 2021 Feb 23;22(4)
International journal of molecular sciences 2021 Feb 23;22(4)
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Cell metabolism 2021 Feb 2;33(2):350-366.e7
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Deng Y, Tong J, Shi W, Tian Z, Yu B, Tang J
Annals of medicine 2021 Dec;53(1):1129-1141
Annals of medicine 2021 Dec;53(1):1129-1141
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477
Cell calcium 2021 Dec;100:102477
Evaluation of plasma exosomal miRNAs as potential diagnostic biomarkers of lymph node metastasis in papillary thyroid carcinoma.
Chen W, Li G, Li Z, Zhu J, Wei T, Lei J
Endocrine 2021 Dec 1;
Endocrine 2021 Dec 1;
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Liu SJ, Meng MY, Han S, Gao H, Zhao YY, Yang Y, Lin ZY, Yang LR, Zhu K, Han R, Huang WW, Wang RQ, Yang LL, Wang WJ, Li L, Wang XD, Hou ZL, Liao LW, Yang L
Rejuvenation research 2021 Aug;24(4):283-293
Rejuvenation research 2021 Aug;24(4):283-293
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Zhao Y, He L, Wang T, Zhu L, Yan N
Metabolites 2021 Aug 23;11(8)
Metabolites 2021 Aug 23;11(8)
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Japanese encephalitis virus manipulates lysosomes membrane for RNA replication and utilizes autophagy components for intracellular growth.
Xu Q, Huang L, Xing J, Zhang J, Li H, Liu L, Hu C, Liao M, Yue J, Qi W
Veterinary microbiology 2021 Apr;255:109025
Veterinary microbiology 2021 Apr;255:109025
Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma.
Cao B, Wang P, Gu L, Liu J
Oncology letters 2021 Apr;21(4):249
Oncology letters 2021 Apr;21(4):249
STING regulates BCR signaling in normal and malignant B cells.
Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA
Cellular & molecular immunology 2021 Apr;18(4):1016-1031
Cellular & molecular immunology 2021 Apr;18(4):1016-1031
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells.
Fu G, Lu L, Pan Z, Fan A, Yin F
Regenerative medicine 2021 Apr;16(4):359-372
Regenerative medicine 2021 Apr;16(4):359-372
Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis.
Wang Y, Xu Z, Wang X, Zheng J, Peng L, Zhou Y, Song Y, Lu Z
Aging 2021 Apr 19;13(8):12239-12257
Aging 2021 Apr 19;13(8):12239-12257
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
Torres-Odio S, Lei Y, Gispert S, Maletzko A, Key J, Menissy SS, Wittig I, Auburger G, West AP
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Journal of immunology (Baltimore, Md. : 1950) 2021 Apr 15;206(8):1890-1900
Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage.
Tung SL, Fanelli G, Matthews RI, Bazoer J, Letizia M, Vizcay-Barrena G, Faruqu FN, Philippeos C, Hannen R, Al-Jamal KT, Lombardi G, Smyth LA
Frontiers in cell and developmental biology 2020;8:317
Frontiers in cell and developmental biology 2020;8:317
Mechanism of Sanguinarine in Inhibiting Macrophages to Promote Metastasis and Proliferation of Lung Cancer via Modulating the Exosomes in A549 Cells.
Yu Y, Luo Y, Fang Z, Teng W, Yu Y, Tian J, Guo P, Xu R, Wu J, Li Y
OncoTargets and therapy 2020;13:8989-9003
OncoTargets and therapy 2020;13:8989-9003
Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance.
Wang X, Cheng K, Zhang G, Jia Z, Yu Y, Guo J, Hua Y, Guo F, Li X, Zou W, Sun H, Dong J, Yang Z
Frontiers in oncology 2020;10:960
Frontiers in oncology 2020;10:960
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer.
Ding XQ, Wang ZY, Xia D, Wang RX, Pan XR, Tong JH
Frontiers in oncology 2020;10:1113
Frontiers in oncology 2020;10:1113
GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice.
Li X, Zhang Y, Zhang M, Wang Y
Scientific reports 2020 Sep 30;10(1):16168
Scientific reports 2020 Sep 30;10(1):16168
Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p.
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, Bai X, Liu D, Wang Z
Acta biomaterialia 2020 Sep 1;113:597-613
Acta biomaterialia 2020 Sep 1;113:597-613
Insight into the proteomic profiling of exosomes secreted by human OM-MSCs reveals a new potential therapy.
Xun C, Ge L, Tang F, Wang L, Zhuo Y, Long L, Qi J, Hu L, Duan D, Chen P, Lu M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110584
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110584
Smyd3-PARP16 axis accelerates unfolded protein response and vascular aging.
Yang D, Wang Q, Wei G, Wu J, Zhu YC, Zhu Q, Ni T, Liu X, Zhu YZ
Aging 2020 Nov 3;12(21):21423-21445
Aging 2020 Nov 3;12(21):21423-21445
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Song L, Liu Z, Hu HH, Yang Y, Li TY, Lin ZZ, Ye J, Chen J, Huang X, Liu DT, Zhou J, Shi Y, Zhao H, Xie C, Chen L, Song E, Lin SY, Lin SC
Nature communications 2020 Nov 17;11(1):5842
Nature communications 2020 Nov 17;11(1):5842
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Oncoprotein SND1 hijacks nascent MHC-I heavy chain to ER-associated degradation, leading to impaired CD8+ T cell response in tumor.
Wang Y, Wang X, Cui X, Zhuo Y, Li H, Ha C, Xin L, Ren Y, Zhang W, Sun X, Ge L, Liu X, He J, Zhang T, Zhang K, Yao Z, Yang X, Yang J
Science advances 2020 May;6(22)
Science advances 2020 May;6(22)
Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer.
Deng Q, Fang Q, Xie B, Sun H, Bao Y, Zhou S
Aging 2020 May 6;12(9):8001-8015
Aging 2020 May 6;12(9):8001-8015
HPV + HNSCC-derived exosomal miR-9 induces macrophage M1 polarization and increases tumor radiosensitivity.
Tong F, Mao X, Zhang S, Xie H, Yan B, Wang B, Sun J, Wei L
Cancer letters 2020 May 28;478:34-44
Cancer letters 2020 May 28;478:34-44
Liver-derived exosome-laden lncRNA MT1DP aggravates cadmium-induced nephrotoxicity.
Gao M, Dong Z, Sun J, Liu W, Xu M, Li C, Zhu P, Yang X, Shang X, Wu Y, Liu S
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Environmental pollution (Barking, Essex : 1987) 2020 Mar;258:113717
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
Zhao F, Cheng L, Shao Q, Chen Z, Lv X, Li J, He L, Sun Y, Ji Q, Lu P, Ji Y, Ji J
Scientific reports 2020 Mar 6;10(1):4197
Scientific reports 2020 Mar 6;10(1):4197
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin.
Uzureau S, Lecordier L, Uzureau P, Hennig D, Graversen JH, Homblé F, Mfutu PE, Oliveira Arcolino F, Ramos AR, La Rovere RM, Luyten T, Vermeersch M, Tebabi P, Dieu M, Cuypers B, Deborggraeve S, Rabant M, Legendre C, Moestrup SK, Levtchenko E, Bultynck G, Erneux C, Pérez-Morga D, Pays E
Cell reports 2020 Mar 17;30(11):3821-3836.e13
Cell reports 2020 Mar 17;30(11):3821-3836.e13
Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling.
Xu L, Faruqu FN, Liam-Or R, Abu Abed O, Li D, Venner K, Errington RJ, Summers H, Wang JT, Al-Jamal KT
Journal of extracellular vesicles 2020 Jun 19;9(1):1779458
Journal of extracellular vesicles 2020 Jun 19;9(1):1779458
The protective effects of human umbilical cord mesenchymal stem cell-derived extracellular vesicles on cisplatin-damaged granulosa cells.
Zhang J, Yin H, Jiang H, Du X, Yang Z
Taiwanese journal of obstetrics & gynecology 2020 Jul;59(4):527-533
Taiwanese journal of obstetrics & gynecology 2020 Jul;59(4):527-533
Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation.
Faruqu FN, Zhou S, Sami N, Gheidari F, Lu H, Al-Jamal KT
FASEB bioAdvances 2020 Jul;2(7):419-433
FASEB bioAdvances 2020 Jul;2(7):419-433
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum.
Li M, Wang J, Fu L, Lu Y, Xu J, Zhou L, Zhu H, Fang L, Feng Z, Xie T, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 15;26:e920376
SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
Li N, Luo X, Yu Q, Yang P, Chen Z, Wang X, Jiang J, Xu J, Gong Q, Eizirik DL, Zhou Z, Zhao J, Xiong F, Zhang S, Wang CY
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Journal of molecular medicine (Berlin, Germany) 2020 Dec;98(12):1795-1807
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling.
Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, Kang D, Liu X, Gao C, Wang PH
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Signal transduction and targeted therapy 2020 Dec 28;5(1):299
Polyethylene Glycol 35 (PEG35) Modulates Exosomal Uptake and Function.
Ferrero-Andrés A, Closa D, Roselló-Catafau J, Folch-Puy E
Polymers 2020 Dec 18;12(12)
Polymers 2020 Dec 18;12(12)
Mycobacterium tuberculosis MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response.
Sun Y, Zhang W, Dong C, Xiong S
mBio 2020 Dec 1;11(6)
mBio 2020 Dec 1;11(6)
SCYL1 arginine methylation by PRMT1 is essential for neurite outgrowth via Golgi morphogenesis.
Amano G, Matsuzaki S, Mori Y, Miyoshi K, Han S, Shikada S, Takamura H, Yoshimura T, Katayama T
Molecular biology of the cell 2020 Aug 15;31(18):1963-1973
Molecular biology of the cell 2020 Aug 15;31(18):1963-1973
USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.
Niu K, Fang H, Chen Z, Zhu Y, Tan Q, Wei D, Li Y, Balajee AS, Zhao Y
Autophagy 2020 Apr;16(4):724-734
Autophagy 2020 Apr;16(4):724-734
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Zheng D, Chen Y, Ai S, Zhang R, Gao Z, Liang C, Cao L, Chen Y, Hong Z, Shi Y, Wang L, Li X, Yang Z
Research (Washington, D.C.) 2019;2019:4803624
Research (Washington, D.C.) 2019;2019:4803624
Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.
Bersuker K, Olzmann JA
Methods in molecular biology (Clifton, N.J.) 2019;2008:57-72
Methods in molecular biology (Clifton, N.J.) 2019;2008:57-72
Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation.
Yan H, Gao Y, Ding Q, Liu J, Li Y, Jin M, Xu H, Ma S, Wang X, Zeng W, Chen Y
International journal of biological sciences 2019;15(7):1368-1382
International journal of biological sciences 2019;15(7):1368-1382
Proteomic analysis of seminal extracellular vesicle proteins involved in asthenozoospermia by iTRAQ.
Lin Y, Liang A, He Y, Li Z, Li Z, Wang G, Sun F
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Molecular reproduction and development 2019 Sep;86(9):1094-1105
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Merriman C, Fu D
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006
Protective effect of Barbaloin in a rat model of myocardial ischemia reperfusion injury through the regulation of the CNPY2‑PERK pathway.
Cui Y, Wang Y, Liu G
International journal of molecular medicine 2019 May;43(5):2015-2023
International journal of molecular medicine 2019 May;43(5):2015-2023
Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.
McKay EC, Beck JS, Khoo SK, Dykema KJ, Cottingham SL, Winn ME, Paulson HL, Lieberman AP, Counts SE
Journal of neuropathology and experimental neurology 2019 May 1;78(5):436-452
Journal of neuropathology and experimental neurology 2019 May 1;78(5):436-452
Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection.
Wang J, Teng Y, Zhao G, Li F, Hou A, Sun B, Kong W, Gao F, Cai L, Jiang C
International journal of molecular sciences 2019 Mar 27;20(7)
International journal of molecular sciences 2019 Mar 27;20(7)
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Two novel ANK1 loss-of-function mutations in Chinese families with hereditary spherocytosis.
Hao L, Li S, Ma D, Chen S, Zhang B, Xiao D, Zhang J, Jiang N, Jiang S, Ma J
Journal of cellular and molecular medicine 2019 Jun;23(6):4454-4463
Journal of cellular and molecular medicine 2019 Jun;23(6):4454-4463
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW
Molecular cell 2019 Jun 6;74(5):891-908.e10
Molecular cell 2019 Jun 6;74(5):891-908.e10
Microglia as modulators of exosomal alpha-synuclein transmission.
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, Kou L, Yin S, Liu L, Huang J, Xiong N, Wang T
Cell death & disease 2019 Feb 20;10(3):174
Cell death & disease 2019 Feb 20;10(3):174
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway.
Wang S, Su X, Xu M, Xiao X, Li X, Li H, Keating A, Zhao RC
Stem cell research & therapy 2019 Apr 11;10(1):117
Stem cell research & therapy 2019 Apr 11;10(1):117
Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways.
Song M, Han L, Chen FF, Wang D, Wang F, Zhang L, Wang ZH, Zhong M, Tang MX, Zhang W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1416-1432
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1416-1432
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Li M, Du W, Zhou M, Zheng L, Song E, Hou J
Biophysics reports 2018;4(6):329-338
Biophysics reports 2018;4(6):329-338
Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway.
Zhou X, Yan T, Huang C, Xu Z, Wang L, Jiang E, Wang H, Chen Y, Liu K, Shao Z, Shang Z
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
Journal of experimental & clinical cancer research : CR 2018 Oct 3;37(1):242
In Vivo Tracking of Multiple Tumor Exosomes Labeled by Phospholipid-Based Bioorthogonal Conjugation.
Zhang P, Dong B, Zeng E, Wang F, Jiang Y, Li D, Liu D
Analytical chemistry 2018 Oct 2;90(19):11273-11279
Analytical chemistry 2018 Oct 2;90(19):11273-11279
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Zhao N, Mi L, Zhang X, Xu M, Yu H, Liu Z, Liu X, Guan G, Gao W, Wang J
Journal of molecular and cellular cardiology 2018 May;118:36-45
Journal of molecular and cellular cardiology 2018 May;118:36-45
Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC
Nature communications 2018 May 15;9(1):1916
Nature communications 2018 May 15;9(1):1916
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Xin X, Wang H, Han L, Wang M, Fang H, Hao Y, Li J, Zhang H, Zheng C, Shen C
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA
Molecular biology of the cell 2018 May 1;29(9):1021-1030
Molecular biology of the cell 2018 May 1;29(9):1021-1030
A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation.
Tesi B, Rascon J, Chiang SCC, Burnyte B, Löfstedt A, Fasth A, Heizmann M, Juozapaite S, Kiudeliene R, Kvedaraite E, Miseviciene V, Muleviciene A, Müller ML, Nordenskjöld M, Matuzeviciene R, Samaitiene R, Speckmann C, Stankeviciene S, Zekas V, Voss M, Ehl S, Vaiciene-Magistris N, Henter JI, Meeths M, Bryceson YT
The Journal of allergy and clinical immunology 2018 Jul;142(1):317-321.e8
The Journal of allergy and clinical immunology 2018 Jul;142(1):317-321.e8
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
Ganji R, Mukkavalli S, Somanji F, Raman M
Molecular and cellular biology 2018 Jul 1;38(13)
Molecular and cellular biology 2018 Jul 1;38(13)
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.
Bersuker K, Peterson CWH, To M, Sahl SJ, Savikhin V, Grossman EA, Nomura DK, Olzmann JA
Developmental cell 2018 Jan 8;44(1):97-112.e7
Developmental cell 2018 Jan 8;44(1):97-112.e7
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Luo H, Jiang M, Lian G, Liu Q, Shi M, Li TY, Song L, Ye J, He Y, Yao L, Zhang C, Lin ZZ, Zhang CS, Zhao TJ, Jia WP, Li P, Lin SY, Lin SC
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Zhang Z, Meszaros G, He WT, Xu Y, de Fatima Magliarelli H, Mailly L, Mihlan M, Liu Y, Puig Gámez M, Goginashvili A, Pasquier A, Bielska O, Neven B, Quartier P, Aebersold R, Baumert TF, Georgel P, Han J, Ricci R
The Journal of experimental medicine 2017 Sep 4;214(9):2671-2693
The Journal of experimental medicine 2017 Sep 4;214(9):2671-2693
Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis.
Komaki M, Numata Y, Morioka C, Honda I, Tooi M, Yokoyama N, Ayame H, Iwasaki K, Taki A, Oshima N, Morita I
Stem cell research & therapy 2017 Oct 3;8(1):219
Stem cell research & therapy 2017 Oct 3;8(1):219
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, Song Y
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.
Li P, Du J, Goodier JL, Hou J, Kang J, Kazazian HH Jr, Zhao K, Yu XF
Nucleic acids research 2017 May 5;45(8):4619-4631
Nucleic acids research 2017 May 5;45(8):4619-4631
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Bonjoch L, Gironella M, Iovanna JL, Closa D
Scientific reports 2017 Jun 9;7(1):3143
Scientific reports 2017 Jun 9;7(1):3143
Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.
De Franco E, Flanagan SE, Yagi T, Abreu D, Mahadevan J, Johnson MB, Jones G, Acosta F, Mulaudzi M, Lek N, Oh V, Petz O, Caswell R, Ellard S, Urano F, Hattersley AT
Diabetes 2017 Jul;66(7):2044-2053
Diabetes 2017 Jul;66(7):2044-2053
DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.
Ding J, Shao L, Yao Y, Tong X, Liu H, Yue S, Xie L, Cheng SY
Scientific reports 2017 Jul 13;7(1):5296
Scientific reports 2017 Jul 13;7(1):5296
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M
Nature immunology 2017 Aug;18(8):899-910
Nature immunology 2017 Aug;18(8):899-910
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Bonjoch L, Casas V, Carrascal M, Closa D
The Journal of pathology 2016 Oct;240(2):235-45
The Journal of pathology 2016 Oct;240(2):235-45
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Zhou Y, Xiong L, Zhang Y, Yu R, Jiang X, Xu G
Journal of proteomics 2016 Oct 4;148:94-104
Journal of proteomics 2016 Oct 4;148:94-104
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
International journal of molecular sciences 2016 Oct 27;17(11)
International journal of molecular sciences 2016 Oct 27;17(11)
Modulation of membrane phosphoinositide dynamics by the phosphatidylinositide 4-kinase activity of the Legionella LepB effector.
Dong N, Niu M, Hu L, Yao Q, Zhou R, Shao F
Nature microbiology 2016 Dec 12;2:16236
Nature microbiology 2016 Dec 12;2:16236
Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer.
Wang X, Xu C, Hua Y, Sun L, Cheng K, Jia Z, Han Y, Dong J, Cui Y, Yang Z
Journal of experimental & clinical cancer research : CR 2016 Dec 1;35(1):186
Journal of experimental & clinical cancer research : CR 2016 Dec 1;35(1):186
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Yang XX, Xu F, Wang D, Yang ZW, Tan HR, Shang MY, Wang X, Cai SQ
Journal of chromatography. A 2015 Sep 25;1413:33-46
Journal of chromatography. A 2015 Sep 25;1413:33-46
Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.
Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ
Genetics 2015 May;200(1):221-35
Genetics 2015 May;200(1):221-35
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Zhu X, He Z, Yuan J, Wen W, Huang X, Hu Y, Lin C, Pan J, Li R, Deng H, Liao S, Zhou R, Wu J, Li J, Li M
Cellular microbiology 2015 Jan;17(1):105-18
Cellular microbiology 2015 Jan;17(1):105-18
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X
Parasitology research 2015 Feb;114(2):659-70
Parasitology research 2015 Feb;114(2):659-70
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3.
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, Chen F, Yang C, Zhou Z, Su SS, Zheng X, Zhang Z, Zhong CQ, Wan H, Xiao M, Lin X, Feng XH, Han J
Nature cell biology 2015 Apr;17(4):434-44
Nature cell biology 2015 Apr;17(4):434-44
PolyC-binding protein 1 interacts with 5'-untranslated region of enterovirus 71 RNA in membrane-associated complex to facilitate viral replication.
Luo Z, Dong X, Li Y, Zhang Q, Kim C, Song Y, Kang L, Liu Y, Wu K, Wu J
PloS one 2014;9(1):e87491
PloS one 2014;9(1):e87491
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy.
Ota K, Obayashi M, Ozaki K, Ichinose S, Kakita A, Tada M, Takahashi H, Ando N, Eishi Y, Mizusawa H, Ishikawa K
Acta neuropathologica communications 2014 Sep 11;2:136
Acta neuropathologica communications 2014 Sep 11;2:136
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Gerondopoulos A, Bastos RN, Yoshimura S, Anderson R, Carpanini S, Aligianis I, Handley MT, Barr FA
The Journal of cell biology 2014 Jun 9;205(5):707-20
The Journal of cell biology 2014 Jun 9;205(5):707-20
Reduced expression of members of the mhc-i antigen processing machinery in ethnic Uighur women with cervical cancer in the Xinjiang region of China.
Haimiti A, Hailiman Y, Gulina A, Du J, Hao Z, Rong XL, Zainuer A, Qin W, Lalai S
Current oncology (Toronto, Ont.) 2014 Feb;21(1):e67-74
Current oncology (Toronto, Ont.) 2014 Feb;21(1):e67-74
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
Tan YL, Genereux JC, Pankow S, Aerts JM, Yates JR 3rd, Kelly JW
Chemistry & biology 2014 Aug 14;21(8):967-76
Chemistry & biology 2014 Aug 14;21(8):967-76
Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis.
Shang Y, Wang F, Bai C, Huang Y, Zhao LJ, Yao XP, Li Q, Sun SH
Chinese medical journal 2011 Jan;124(1):38-44
Chinese medical journal 2011 Jan;124(1):38-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10427-2-AP(CANX antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A431 cells, using CANX antibody 10427-2-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10427-2-AP(CANX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10427-2-AP(CANX antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Calnexin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Calnexin. This antibody recognizes human,mouse,rat antigen. The Calnexin antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
