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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- AB0037-500 - Provider product page
- Provider
- SICGEN
- Proper citation
- SICGEN Cat#AB0037-500, RRID:AB_2333118
- Product name
- Anti-CANX
- Antibody type
- Polyclonal
- Description
- Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 1 mg
- Concentration
- 2 mg/ml
- Storage
- Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance.
Host cell autophagy contributes to Plasmodium liver development.
Rodrigues T, Matafome P, Sereno J, Almeida J, Castelhano J, Gamas L, Neves C, Gonçalves S, Carvalho C, Arslanagic A, Wilcken E, Fonseca R, Simões I, Conde SV, Castelo-Branco M, Seiça R
Scientific reports 2017 May 10;7(1):1698
Scientific reports 2017 May 10;7(1):1698
Host cell autophagy contributes to Plasmodium liver development.
Thieleke-Matos C, Lopes da Silva M, Cabrita-Santos L, Portal MD, Rodrigues IP, Zuzarte-Luis V, Ramalho JS, Futter CE, Mota MM, Barral DC, Seabra MC
Cellular microbiology 2016 Mar;18(3):437-50
Cellular microbiology 2016 Mar;18(3):437-50
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Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- Lysates at 50 µg per lane
- Sample type
- 3T3, Raw264.7, Hepa1-6
- Primary Ab dilution
- 1/500
- Conjugate
- Horseradish Peroxidase
- Secondary Ab
- Secondary Ab
- Secondary Ab dilution
- 1/10,000
Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- Cells fixed with 4% of PFA
- Sample type
- Hepa1-6
- Primary Ab dilution
- 1/100
- Conjugate
- Green dye
