Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations [0]
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- Product number
- V3033 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- CD70 Antibody
- Antibody type
- Monoclonal
- Antigen
- The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- BU69
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CD70 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Clinical significance of CD70 expression on T cells in human T-lymphotropic virus type-1 carriers and adult T cell leukemia/ lymphoma patients.
Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab.
High functional CD70 expression on α-type 1-polarized dendritic cells from patients with chronic lymphocytic leukaemia.
CD27(+)CD56Bright natural killer cells may be involved in spontaneous clearance of acute hepatitis C in HIV-positive patients.
CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death.
Soluble CD27 induces IgG production through activation of antigen-primed B cells.
Irradiation enhances human T-cell function by upregulating CD70 expression on antigen-presenting cells in vitro.
Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation.
Homotypic T-cell/T-cell interaction induces T-cell activation, proliferation, and differentiation.
Helper B cells promote cytotoxic T cell survival and proliferation independently of antigen presentation through CD27/CD70 interactions.
Masamoto I, Yoshimitsu M, Kuroki A, Horai S, Ezinne CC, Kozako T, Hachiman M, Kamada Y, Baba M, Arima N
Leukemia & lymphoma 2016 Mar;57(3):685-91
Leukemia & lymphoma 2016 Mar;57(3):685-91
Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab.
Ramakrishna V, Sundarapandiyan K, Zhao B, Bylesjo M, Marsh HC, Keler T
Journal for immunotherapy of cancer 2015;3:37
Journal for immunotherapy of cancer 2015;3:37
High functional CD70 expression on α-type 1-polarized dendritic cells from patients with chronic lymphocytic leukaemia.
Junevik K, Werlenius O, Fogelstrand L, Karlsson-Parra A, Andersson PO
Scandinavian journal of immunology 2014 Jun;79(6):415-22
Scandinavian journal of immunology 2014 Jun;79(6):415-22
CD27(+)CD56Bright natural killer cells may be involved in spontaneous clearance of acute hepatitis C in HIV-positive patients.
Eisenhardt M, Glässner A, Wolter F, Krämer B, Kokordelis P, Nischalke HD, Boesecke C, Rockstroh JK, Spengler U, Nattermann J
AIDS (London, England) 2014 Aug 24;28(13):1879-84
AIDS (London, England) 2014 Aug 24;28(13):1879-84
CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death.
Lee EM, Hurh S, Cho B, Oh KH, Kim SU, Surh CD, Sprent J, Yang J, Kim JY, Ahn C
Stem cell research & therapy 2013 May 21;4(3):56
Stem cell research & therapy 2013 May 21;4(3):56
Soluble CD27 induces IgG production through activation of antigen-primed B cells.
Dang LV, Nilsson A, Ingelman-Sundberg H, Cagigi A, Gelinck LB, Titanji K, De Milito A, Grutzmeier S, Hedlund J, Kroon FP, Chiodi F
Journal of internal medicine 2012 Mar;271(3):282-93
Journal of internal medicine 2012 Mar;271(3):282-93
Irradiation enhances human T-cell function by upregulating CD70 expression on antigen-presenting cells in vitro.
Huang J, Wang QJ, Yang S, Li YF, El-Gamil M, Rosenberg SA, Robbins PF
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011 May;34(4):327-35
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011 May;34(4):327-35
Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation.
Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T
Immunology 2010 May;130(1):137-49
Immunology 2010 May;130(1):137-49
Homotypic T-cell/T-cell interaction induces T-cell activation, proliferation, and differentiation.
Ramming A, Thümmler K, Schulze-Koops H, Skapenko A
Human immunology 2009 Nov;70(11):873-81
Human immunology 2009 Nov;70(11):873-81
Helper B cells promote cytotoxic T cell survival and proliferation independently of antigen presentation through CD27/CD70 interactions.
Deola S, Panelli MC, Maric D, Selleri S, Dmitrieva NI, Voss CY, Klein H, Stroncek D, Wang E, Marincola FM
Journal of immunology (Baltimore, Md. : 1950) 2008 Feb 1;180(3):1362-72
Journal of immunology (Baltimore, Md. : 1950) 2008 Feb 1;180(3):1362-72
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