BS8321

antibody from Bioworld Technology, Inc
Targeting: CNMD BRICD3, CHM-I, CHM1, LECT1, MYETS1
Provider product page for BS8321
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8321 - Provider product page
Provider
Bioworld Technology, Inc
Product name
LECT1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human LECT1.
Description
ChM-1 is a cartilage-specific matrix glycoprotein that stimulates the growth of chondrocytes. ChM-1 inhibits angiogenesis by disrupting the tube formation of endothelial cells and thus is responsible for the avascular nature of cartilage. ChM-1 is strongly expressed by the proliferating and hypertrophic zones in the epiphyseal plate of long bones. ChM-1 accumulates in the interterritorial matrix around the lacunae. During development, downregulation of ChM-1 permits angiogenesis and ultimately bone formation on the cartilage template. ChM-1 expression is downregulated in the presence of several growth factors including TGFÉÇ2, FGF2 and PTHLH. ChM-1 expression may also play a role in the hypovascularity and chondroid formation of pleomorphic adenomas. The gene encoding human ChM-1 maps to chromosome 13q14-q21.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CNMD protein structure - BS8321 shown in red.