Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB2229G - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Nectin-2/CD112 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Nectin-2/CD112 by flow cytometry.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1.
Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.
Walwyn-Brown K, Guldevall K, Saeed M, Pende D, Önfelt B, MacDonald AS, Davis DM
Journal of immunology (Baltimore, Md. : 1950) 2018 Oct 1;201(7):2028-2041
Journal of immunology (Baltimore, Md. : 1950) 2018 Oct 1;201(7):2028-2041
Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.
Kearney CJ, Ramsbottom KM, Voskoboinik I, Darcy PK, Oliaro J
Oncoimmunology 2016 Aug;5(8):e1196308
Oncoimmunology 2016 Aug;5(8):e1196308
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Detection of Nectin-2/CD112 in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human Nectin-2/CD112 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB2229G, filled histogram) or isotype control antibody (Catalog # IC002G, open histogram). View our protocol for Staining Membrane-associated Proteins.