CABT-L1711M

antibody from Creative Diagnostics

Targeting: IL15RA CD215, IL-15RA

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-L1711M

Provider

Creative Diagnostics

Product name

Mouse Anti-Human IL15RA monoclonal antibody, clone 2D6

Antibody type

Monoclonal

Description

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2D6

Vial size

100 ug

Concentration

Lot specific

Storage

Short Term: 2-8°C. Long Term: -20°C. Avoid repeated freezing and thawing.