ABIN951910

antibody from antibodies-online

Targeting: DIAPH3 AN, AUNA1, DRF3, FLJ34705, NSDAN

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN951910

Provider

antibodies-online

Product name

anti-Diaphanous Homolog 3 (Drosophila) (DIAPH3) (AA 1060-1090), (C-Term) antibody

Antibody type

Polyclonal

Description

Affinity Chromatography on Protein A

Reactivity

Human

Host

Rabbit

Epitope

C-Term, AA 1060-1090

Vial size

0.4 mL

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division.

DeWard AD, Alberts AS
The Journal of biological chemistry 2009 Jul 24;284(30):20061-9

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Filopodia formation induced by active mDia2/Drf3.

Block J, Stradal TE, Hänisch J, Geffers R, Köstler SA, Urban E, Small JV, Rottner K, Faix J
Journal of microscopy 2008 Sep;231(3):506-17

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WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2.

Beli P, Mascheroni D, Xu D, Innocenti M
Nature cell biology 2008 Jul;10(7):849-57

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mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration.

Gupton SL, Eisenmann K, Alberts AS, Waterman-Storer CM
Journal of cell science 2007 Oct 1;120(Pt 19):3475-87

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB