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- Antibody Data
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- References [4]
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- Western blot [1]
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- Product number
- NB110-38884 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-38884, RRID:AB_2249359
- Product name
- Rabbit Polyclonal Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ul
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas.
Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis.
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.
Ratovitski EA
Cell cycle (Georgetown, Tex.) 2014;13(5):749-61
Cell cycle (Georgetown, Tex.) 2014;13(5):749-61
Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis.
Walsh CA, Bolger JC, Byrne C, Cocchiglia S, Hao Y, Fagan A, Qin L, Cahalin A, McCartan D, McIlroy M, O'Gaora P, Xu J, Hill AD, Young LS
Cancer research 2014 May 1;74(9):2533-44
Cancer research 2014 May 1;74(9):2533-44
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Luo W, Chang R, Zhong J, Pandey A, Semenza GL
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 4;109(49):E3367-76
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 4;109(49):E3367-76
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.
Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S
The EMBO journal 2012 Apr 18;31(8):1865-78
The EMBO journal 2012 Apr 18;31(8):1865-78
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody [NB110-38884] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-JMJD2C antibody NB110-38884 lot 2 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. JMJD2C was also immunoprecipitated by rabbit anti-JMJD2C antibody NB110-38884 Lot 1. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).
