Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR02505G - Provider product page
- Provider
- Leading Biology
- Product name
- DNAJA3 / TID1 Antibody (C-Terminus)
- Antibody type
- Polyclonal
- Description
- Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma- mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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