Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11885-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11885-1-AP, RRID:AB_2191458
- Product name
- SLC4A4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SLC4A4 antibody (Cat. #11885-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functional Characterization of a Novel SLC4A4 Variant and Uniparental Isodisomy in Proximal Renal Tubular Acidosis Patient.
Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells.
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.
Acid-base effects of combined renal deletion of NBCe1-A and NBCe1-B.
Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel.
Bicarbonate ion transport by the electrogenic Na(+) /HCO(3)(-) cotransporter, NBCe1, is required for normal electrical slow-wave activity in mouse small intestine.
Role of the renal androgen receptor in sex differences in ammonia metabolism.
Modulation of Tubular pH by Acetazolamide in a Ca(2+) Transport Deficient Mice Facilitates Calcium Nephrolithiasis.
Expression of the regulated isoform of the electrogenic Na(+)/HCO(3)(-) cotransporter, NBCe1, is enriched in pacemaker interstitial cells of Cajal.
Acetazolamide causes renal [Formula: see text] wasting but inhibits ammoniagenesis and prevents the correction of metabolic acidosis by the kidney.
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice.
NBCe1-A is required for the renal ammonia and K(+) response to hypokalemia.
Testosterone modulates renal ammonia metabolism.
Differences in acidosis-stimulated renal ammonia metabolism in the male and female kidney.
Evidence for a regulated Ca(2+) entry in proximal tubular cells and its implication in calcium stone formation.
Haploinsufficiency of the Mouse Atp6v1b1 Gene Leads to a Mild Acid-Base Disturbance with Implications for Kidney Stone Disease.
Expression of the B splice variant of NBCe1 (SLC4A4) in the mouse kidney.
Differences in renal ammonia metabolism in male and female kidney.
Expression of sodium-dependent dicarboxylate transporter 1 (NaDC1/SLC13A2) in normal and neoplastic human kidney.
Proximal tubule-specific glutamine synthetase deletion alters basal and acidosis-stimulated ammonia metabolism.
Liu Y, Sheng W, Hou S, Hou M, Zhang Y, Wang X, Zhang S, Zhou F, Cai C, Wang W
Biochemical genetics 2024 Aug;62(4):2469-2481
Biochemical genetics 2024 Aug;62(4):2469-2481
Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells.
Shin S, Awuah Boadi E, Bandyopadhyay BC
Clinical and experimental pharmacology & physiology 2023 Mar;50(3):247-255
Clinical and experimental pharmacology & physiology 2023 Mar;50(3):247-255
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Luo S, Li Y, Li S, Jiang R, Deng F, Liu G, Zhang J
Frontiers in physiology 2022;13:856427
Frontiers in physiology 2022;13:856427
The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.
Ali ES, LipoĊska A, O'Hara BP, Amici DR, Torno MD, Gao P, Asara JM, Yap MF, Mendillo ML, Ben-Sahra I
Molecular cell 2022 Sep 1;82(17):3284-3298.e7
Molecular cell 2022 Sep 1;82(17):3284-3298.e7
Acid-base effects of combined renal deletion of NBCe1-A and NBCe1-B.
Lee HW, Verlander JW, Shull GE, Harris AN, Weiner ID
American journal of physiology. Renal physiology 2022 Feb 1;322(2):F208-F224
American journal of physiology. Renal physiology 2022 Feb 1;322(2):F208-F224
Selective Deletion of the Mechanistic Target of Rapamycin From the Renal Collecting Duct Principal Cell in Mice Down-Regulates the Epithelial Sodium Channel.
Chen B, Fluitt MB, Brown AL, Scott S, Gadicherla A, Ecelbarger CM
Frontiers in physiology 2021;12:787521
Frontiers in physiology 2021;12:787521
Bicarbonate ion transport by the electrogenic Na(+) /HCO(3)(-) cotransporter, NBCe1, is required for normal electrical slow-wave activity in mouse small intestine.
Zhao W, Zhang L, Ermilov LG, Colmenares Aguilar MG, Linden DR, Eisenman ST, Romero MF, Farrugia G, Sha L, Gibbons SJ
Neurogastroenterology and motility 2021 Sep;33(9):e14149
Neurogastroenterology and motility 2021 Sep;33(9):e14149
Role of the renal androgen receptor in sex differences in ammonia metabolism.
Harris AN, Castro RA, Lee HW, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F629-F644
American journal of physiology. Renal physiology 2021 Nov 1;321(5):F629-F644
Modulation of Tubular pH by Acetazolamide in a Ca(2+) Transport Deficient Mice Facilitates Calcium Nephrolithiasis.
Awuah Boadi E, Shin S, Yeroushalmi S, Choi BE, Li P, Bandyopadhyay BC
International journal of molecular sciences 2021 Mar 17;22(6)
International journal of molecular sciences 2021 Mar 17;22(6)
Expression of the regulated isoform of the electrogenic Na(+)/HCO(3)(-) cotransporter, NBCe1, is enriched in pacemaker interstitial cells of Cajal.
Colmenares Aguilar MG, Mazzone A, Eisenman ST, Strege PR, Bernard CE, Holmes HL, Romero MF, Farrugia G, Gibbons SJ
American journal of physiology. Gastrointestinal and liver physiology 2021 Jan 1;320(1):G93-G107
American journal of physiology. Gastrointestinal and liver physiology 2021 Jan 1;320(1):G93-G107
Acetazolamide causes renal [Formula: see text] wasting but inhibits ammoniagenesis and prevents the correction of metabolic acidosis by the kidney.
Alam P, Amlal S, Thakar CV, Amlal H
American journal of physiology. Renal physiology 2020 Sep 1;319(3):F366-F379
American journal of physiology. Renal physiology 2020 Sep 1;319(3):F366-F379
Neddylation-mediated Nedd4-2 activation regulates ubiquitination modification of renal NBCe1.
Tu J, Zhang B, Fang G, Chang W, Zhao Y
Experimental cell research 2020 May 15;390(2):111958
Experimental cell research 2020 May 15;390(2):111958
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice.
Aljaylani A, Fluitt M, Piselli A, Shepard BD, Tiwari S, Ecelbarger CM
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2020 Jul 18;54(4):682-695
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2020 Jul 18;54(4):682-695
NBCe1-A is required for the renal ammonia and K(+) response to hypokalemia.
Lee HW, Harris AN, Romero MF, Welling PA, Wingo CS, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F402-F421
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F402-F421
Testosterone modulates renal ammonia metabolism.
Harris AN, Lee HW, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F922-F935
American journal of physiology. Renal physiology 2020 Apr 1;318(4):F922-F935
Differences in acidosis-stimulated renal ammonia metabolism in the male and female kidney.
Harris AN, Lee HW, Fang L, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2019 Oct 1;317(4):F890-F905
American journal of physiology. Renal physiology 2019 Oct 1;317(4):F890-F905
Evidence for a regulated Ca(2+) entry in proximal tubular cells and its implication in calcium stone formation.
Ibeh CL, Yiu AJ, Kanaras YL, Paal E, Birnbaumer L, Jose PA, Bandyopadhyay BC
Journal of cell science 2019 Apr 30;132(9)
Journal of cell science 2019 Apr 30;132(9)
Haploinsufficiency of the Mouse Atp6v1b1 Gene Leads to a Mild Acid-Base Disturbance with Implications for Kidney Stone Disease.
Bourgeois S, Bettoni C, Baron S, Wagner CA
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(3):1095-1107
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(3):1095-1107
Expression of the B splice variant of NBCe1 (SLC4A4) in the mouse kidney.
Fang L, Lee HW, Chen C, Harris AN, Romero MF, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2018 Sep 1;315(3):F417-F428
American journal of physiology. Renal physiology 2018 Sep 1;315(3):F417-F428
Differences in renal ammonia metabolism in male and female kidney.
Harris AN, Lee HW, Osis G, Fang L, Webster KL, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2018 Aug 1;315(2):F211-F222
American journal of physiology. Renal physiology 2018 Aug 1;315(2):F211-F222
Expression of sodium-dependent dicarboxylate transporter 1 (NaDC1/SLC13A2) in normal and neoplastic human kidney.
Lee HW, Handlogten ME, Osis G, Clapp WL, Wakefield DN, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2017 Mar 1;312(3):F427-F435
American journal of physiology. Renal physiology 2017 Mar 1;312(3):F427-F435
Proximal tubule-specific glutamine synthetase deletion alters basal and acidosis-stimulated ammonia metabolism.
Lee HW, Osis G, Handlogten ME, Lamers WH, Chaudhry FA, Verlander JW, Weiner ID
American journal of physiology. Renal physiology 2016 Jun 1;310(11):F1229-42
American journal of physiology. Renal physiology 2016 Jun 1;310(11):F1229-42
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 11885-1-AP(SLC4A4 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SLC4A4 antibody 11885-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line