Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2844039 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1-30, N-Term
- Antibody clone number
- RB10077
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer.
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury.
Histone demethylase KDM6B promotes epithelial-mesenchymal transition.
Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs.
Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes.
Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells.
Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells.
Oncogenic RAS alters the global and gene-specific histone modification pattern during epithelial-mesenchymal transition in colorectal carcinoma cells.
Epigenetic analysis of KSHV latent and lytic genomes.
Jmjd3 activates Mash1 gene in RA-induced neuronal differentiation of P19 cells.
Epigenetic regulation of the alternatively activated macrophage phenotype.
Abnormal expression pattern of histone demethylases in CD4(+) T cells of MRL/lpr lupus-like mice.
Liao MY, Kuo MY, Lu TY, Wang YP, Wu HC
International journal of oncology 2015 Apr;46(4):1788-800
International journal of oncology 2015 Apr;46(4):1788-800
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD
Nature medicine 2014 Dec;20(12):1394-6
Nature medicine 2014 Dec;20(12):1394-6
Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury.
Lee K, Na W, Lee JY, Na J, Cho H, Wu H, Yune TY, Kim WS, Ju BG
Journal of neurochemistry 2012 Jul;122(2):272-82
Journal of neurochemistry 2012 Jul;122(2):272-82
Histone demethylase KDM6B promotes epithelial-mesenchymal transition.
Ramadoss S, Chen X, Wang CY
The Journal of biological chemistry 2012 Dec 28;287(53):44508-17
The Journal of biological chemistry 2012 Dec 28;287(53):44508-17
Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs.
Kim SW, Yoon SJ, Chuong E, Oyolu C, Wills AE, Gupta R, Baker J
Developmental biology 2011 Sep 15;357(2):492-504
Developmental biology 2011 Sep 15;357(2):492-504
Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes.
Hyland PL, McDade SS, McCloskey R, Dickson GJ, Arthur K, McCance DJ, Patel D
Journal of virology 2011 Nov;85(21):10999-1006
Journal of virology 2011 Nov;85(21):10999-1006
Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells.
Balasubramanian S, Chew YC, Eckert RL
Molecular pharmacology 2011 Nov;80(5):870-8
Molecular pharmacology 2011 Nov;80(5):870-8
Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells.
Lu TY, Lu RM, Liao MY, Yu J, Chung CH, Kao CF, Wu HC
The Journal of biological chemistry 2010 Mar 19;285(12):8719-32
The Journal of biological chemistry 2010 Mar 19;285(12):8719-32
Oncogenic RAS alters the global and gene-specific histone modification pattern during epithelial-mesenchymal transition in colorectal carcinoma cells.
Peláez IM, Kalogeropoulou M, Ferraro A, Voulgari A, Pankotai T, Boros I, Pintzas A
The international journal of biochemistry & cell biology 2010 Jun;42(6):911-20
The international journal of biochemistry & cell biology 2010 Jun;42(6):911-20
Epigenetic analysis of KSHV latent and lytic genomes.
Toth Z, Maglinte DT, Lee SH, Lee HR, Wong LY, Brulois KF, Lee S, Buckley JD, Laird PW, Marquez VE, Jung JU
PLoS pathogens 2010 Jul 22;6(7):e1001013
PLoS pathogens 2010 Jul 22;6(7):e1001013
Jmjd3 activates Mash1 gene in RA-induced neuronal differentiation of P19 cells.
Dai JP, Lu JY, Zhang Y, Shen YF
Journal of cellular biochemistry 2010 Aug 15;110(6):1457-63
Journal of cellular biochemistry 2010 Aug 15;110(6):1457-63
Epigenetic regulation of the alternatively activated macrophage phenotype.
Ishii M, Wen H, Corsa CA, Liu T, Coelho AL, Allen RM, Carson WF 4th, Cavassani KA, Li X, Lukacs NW, Hogaboam CM, Dou Y, Kunkel SL
Blood 2009 Oct 8;114(15):3244-54
Blood 2009 Oct 8;114(15):3244-54
Abnormal expression pattern of histone demethylases in CD4(+) T cells of MRL/lpr lupus-like mice.
Long H, Huang W, Yin H, Zhao S, Zhao M, Lu Q
Lupus 2009 Dec;18(14):1327-8
Lupus 2009 Dec;18(14):1327-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC