BS7716

antibody from Bioworld Technology, Inc
Targeting: CHIT1 CHI3, CHIT
Provider product page for BS7716
Western blot
Immunohistochemistry

Antibody data

Product number
BS7716 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CHIT1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CHIT1.
Description
Chitinases are ubiquitous chitin-fragmenting hydrolases. The chitinase Chitotriosidase is capable of cleaving natural chitin and chitin-like substrates in humans and may play a role in immunity against pathogens containing chitin. Activated human macrophages secrete chitotriosidase, and increased plasma levels of chitotriosidase are a feature of patients suffering from Gaucher disease. Expression of mouse Chitotriosidase is restricted to brain, skin, bone marrow, kidney, tongue, stomach and testis. The homology between chitotriosidase and chitinases found in lower organisms is significant. Acidic mammalian chitinase precursor (AMCase) degrades chitotriose and chitin. AMCase is highly expressed in stomach tissues and is primarily a secreted protein. It is involved in Th2-mediated inflammation and may play a role in asthma and allergic diseases.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CHIT1 protein structure - BS7716 shown in red.