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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- H00124404-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00124404-B01P, RRID:AB_2187006
- Product name
- Mouse Polyclonal Septin-12 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. Sept 12 - septin 12,
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells.
CDC42 Negatively Regulates Testis-Specific SEPT12 Polymerization.
SEPT12-NDC1 Complexes Are Required for Mammalian Spermiogenesis.
SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells.
SEPT12-microtubule complexes are required for sperm head and tail formation.
SEPTIN12 genetic variants confer susceptibility to teratozoospermia.
SEPT12 mutations cause male infertility with defective sperm annulus.
Kuo PL, Tseng JY, Chen HI, Wu CY, Omar HA, Wang CY, Cheng HY, Hsu CC, Fu TF, Teng YN
Biochimie 2019 Mar;158:1-9
Biochimie 2019 Mar;158:1-9
CDC42 Negatively Regulates Testis-Specific SEPT12 Polymerization.
Huang CY, Wang YY, Chen YL, Chen MF, Chiang HS, Kuo PL, Lin YH
International journal of molecular sciences 2018 Sep 5;19(9)
International journal of molecular sciences 2018 Sep 5;19(9)
SEPT12-NDC1 Complexes Are Required for Mammalian Spermiogenesis.
Lai TH, Wu YY, Wang YY, Chen MF, Wang P, Chen TM, Wu YN, Chiang HS, Kuo PL, Lin YH
International journal of molecular sciences 2016 Nov 16;17(11)
International journal of molecular sciences 2016 Nov 16;17(11)
SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells.
Yeh CH, Kuo PL, Wang YY, Wu YY, Chen MF, Lin DY, Lai TH, Chiang HS, Lin YH
PloS one 2015;10(3):e0120722
PloS one 2015;10(3):e0120722
SEPT12-microtubule complexes are required for sperm head and tail formation.
Kuo PL, Chiang HS, Wang YY, Kuo YC, Chen MF, Yu IS, Teng YN, Lin SW, Lin YH
International journal of molecular sciences 2013 Nov 7;14(11):22102-16
International journal of molecular sciences 2013 Nov 7;14(11):22102-16
SEPTIN12 genetic variants confer susceptibility to teratozoospermia.
Lin YH, Wang YY, Chen HI, Kuo YC, Chiou YW, Lin HH, Wu CM, Hsu CC, Chiang HS, Kuo PL
PloS one 2012;7(3):e34011
PloS one 2012;7(3):e34011
SEPT12 mutations cause male infertility with defective sperm annulus.
Kuo YC, Lin YH, Chen HI, Wang YY, Chiou YW, Lin HH, Pan HA, Wu CM, Su SM, Hsu CC, Kuo PL
Human mutation 2012 Apr;33(4):710-9
Human mutation 2012 Apr;33(4):710-9
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Septin-12 Antibody [H00124404-B01P] - Analysis of SEPT12 expression in transfected 293T cell line by SEPT12 polyclonal antibody. Lane 1: SEPT12 transfected lysate(39.38 KDa). Lane 2: Non-transfected lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: Septin-12 Antibody [H00124404-B01P] - Analysis of purified antibody to SEPT12 on HeLa cell. (antibody concentration 10 ug/ml)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Septin-12 Antibody [H00124404-B01P] - Analysis of purified antibody to SEPT12 on formalin-fixed paraffin-embedded human colon. (antibody concentration 3 ug/ml)
