ABIN185123

antibody from antibodies-online

Targeting: ARHGEF18 KIAA0521, MGC15913, P114-RhoGEF, p114RhoGEF

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN185123

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN185123, RRID:AB_10776736

Product name

anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (C-Term) antibody

Antibody type

Polyclonal

Description

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reactivity

Human, Canine

Host

Goat

Epitope

C-Term

Vial size

100 μg

Storage

Aliquot and store at -20°C.

Handling

Minimize freezing and thawing.

References

Submitted references

ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation.

Herder C, Swiercz JM, Müller C, Peravali R, Quiring R, Offermanns S, Wittbrodt J, Loosli F
Development (Cambridge, England) 2013 Jul;140(13):2787-97

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Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion.

Terry SJ, Elbediwy A, Zihni C, Harris AR, Bailly M, Charras GT, Balda MS, Matter K
PloS one 2012;7(11):e50188

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Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis.

Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K
Nature cell biology 2011 Feb;13(2):159-66

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Identification and characterization of a novel Rho-specific guanine nucleotide exchange factor.

Blomquist A, Schwörer G, Schablowski H, Psoma A, Lehnen M, Jakobs KH, Rümenapp U
The Biochemical journal 2000 Dec 1;352 Pt 2:319-25

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB