10043-2-AP
antibody from Proteintech Group
Targeting: RB1CC1
ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131
Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations [0]
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- Product number
- 10043-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10043-2-AP, RRID:AB_2253571
- Product name
- RB1CC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RB1CC1 antibody (Cat. #10043-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
Alternative mitochondrial quality control mediated by extracellular release.
Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury.
Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.
The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria.
Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants.
ATM functions at the peroxisome to induce pexophagy in response to ROS.
Structure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiation.
Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis.
Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.
Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment.
Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer.
p62/SQSTM1 synergizes with autophagy for tumor growth in vivo.
Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD.
The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling.
Noncanonical autophagy promotes the visual cycle.
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.
Kennedy A, Ren HY, Madden VJ, Cyr DM
Molecular biology of the cell 2022 Aug 1;33(9):ar84
Molecular biology of the cell 2022 Aug 1;33(9):ar84
Alternative mitochondrial quality control mediated by extracellular release.
Choong CJ, Okuno T, Ikenaka K, Baba K, Hayakawa H, Koike M, Yokota M, Doi J, Kakuda K, Takeuchi T, Kuma A, Nakamura S, Nagai Y, Nagano S, Yoshimori T, Mochizuki H
Autophagy 2021 Oct;17(10):2962-2974
Autophagy 2021 Oct;17(10):2962-2974
Repairing and Analgesic Effects of Umbilical Cord Mesenchymal Stem Cell Transplantation in Mice with Spinal Cord Injury.
Wu LL, Pan XM, Chen HH, Fu XY, Jiang J, Ding MX
BioMed research international 2020;2020:7650354
BioMed research international 2020;2020:7650354
Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.
Wandel MP, Kim BH, Park ES, Boyle KB, Nayak K, Lagrange B, Herod A, Henry T, Zilbauer M, Rohde J, MacMicking JD, Randow F
Nature immunology 2020 Aug;21(8):880-891
Nature immunology 2020 Aug;21(8):880-891
The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria.
Ravenhill BJ, Boyle KB, von Muhlinen N, Ellison CJ, Masson GR, Otten EG, Foeglein A, Williams R, Randow F
Molecular cell 2019 Apr 18;74(2):320-329.e6
Molecular cell 2019 Apr 18;74(2):320-329.e6
Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants.
Uematsu M, Nishimura T, Sakamaki Y, Yamamoto H, Mizushima N
Autophagy 2017 Aug 3;13(8):1452-1464
Autophagy 2017 Aug 3;13(8):1452-1464
ATM functions at the peroxisome to induce pexophagy in response to ROS.
Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL
Nature cell biology 2015 Oct;17(10):1259-1269
Nature cell biology 2015 Oct;17(10):1259-1269
Structure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiation.
Suzuki H, Kaizuka T, Mizushima N, Noda NN
Nature structural & molecular biology 2015 Jul;22(7):572-80
Nature structural & molecular biology 2015 Jul;22(7):572-80
Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis.
Wen J, Yeo S, Wang C, Chen S, Sun S, Haas MA, Tu W, Jin F, Guan JL
Breast cancer research and treatment 2015 Feb;149(3):619-29
Breast cancer research and treatment 2015 Feb;149(3):619-29
Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.
Zhong Y, Morris DH, Jin L, Patel MS, Karunakaran SK, Fu YJ, Matuszak EA, Weiss HL, Chait BT, Wang QJ
The Journal of biological chemistry 2014 Sep 19;289(38):26021-26037
The Journal of biological chemistry 2014 Sep 19;289(38):26021-26037
Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment.
Ge L, Zhang M, Schekman R
eLife 2014 Nov 28;3:e04135
eLife 2014 Nov 28;3:e04135
Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer.
Li X, Wan X, Chen H, Yang S, Liu Y, Mo W, Meng D, Du W, Huang Y, Wu H, Wang J, Li T, Li Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 1;20(9):2312-25
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 1;20(9):2312-25
p62/SQSTM1 synergizes with autophagy for tumor growth in vivo.
Wei H, Wang C, Croce CM, Guan JL
Genes & development 2014 Jun 1;28(11):1204-16
Genes & development 2014 Jun 1;28(11):1204-16
Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD.
Ma D, Molusky MM, Song J, Hu CR, Fang F, Rui C, Mathew AV, Pennathur S, Liu F, Cheng JX, Guan JL, Lin JD
Molecular endocrinology (Baltimore, Md.) 2013 Oct;27(10):1643-54
Molecular endocrinology (Baltimore, Md.) 2013 Oct;27(10):1643-54
The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling.
Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G
Developmental biology 2013 May 15;377(2):415-27
Developmental biology 2013 May 15;377(2):415-27
Noncanonical autophagy promotes the visual cycle.
Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, Ablonczy Z, Chan CC, Zhou Z, Green DR, Ferguson TA
Cell 2013 Jul 18;154(2):365-76
Cell 2013 Jul 18;154(2):365-76
Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.
Gammoh N, Florey O, Overholtzer M, Jiang X
Nature structural & molecular biology 2013 Feb;20(2):144-9
Nature structural & molecular biology 2013 Feb;20(2):144-9
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.
Nazio F, Strappazzon F, Antonioli M, Bielli P, Cianfanelli V, Bordi M, Gretzmeier C, Dengjel J, Piacentini M, Fimia GM, Cecconi F
Nature cell biology 2013 Apr;15(4):406-16
Nature cell biology 2013 Apr;15(4):406-16
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.
Wang D, Olman MA, Stewart J Jr, Tipps R, Huang P, Sanders PW, Toline E, Prayson RA, Lee J, Weil RJ, Palmer CA, Gillespie GY, Liu WM, Pieper RO, Guan JL, Gladson CL
PloS one 2011;6(5):e19629
PloS one 2011;6(5):e19629
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.
Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X
The Journal of biological chemistry 2009 May 1;284(18):12297-305
The Journal of biological chemistry 2009 May 1;284(18):12297-305
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