CABT-B9537

antibody from Creative Diagnostics

Targeting: SEMA6D FLJ11598, KIAA1479

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-B9537

Provider

Creative Diagnostics

Product name

Mouse anti-Human SEMA6D monoclonal antibody, clone 368620

Antibody type

Monoclonal

Description

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

368620

Vial size

100 _g

Concentration

0.5 mg/ml

Storage

-20°C, Avoid Freeze/Thaw Cycles